Leukemoid reaction after methotrexate-induced pancytopenia in a patient undergoing continuous ambulatory peritoneal dialysis

Chiao Ying Sun, Hou Chang Lin, Yung Chih Chen, Chi Ren Tsai, Mai Szu Wu

研究成果: 雜誌貢獻文章同行評審

5 引文 斯高帕斯(Scopus)

摘要

Methotrexate has been used as an important alternative therapy in the treatment of various rheumatic diseases. Life threatening marrow suppression in end-stage renal disease patients undergoing hemodialysis or continuous ambulatory peritoneal dialysis has been reported. A 33-year-old woman with systemic lupus erythematosus undergoing chronic peritoneal dialysis developed severe mucositis and pancytopenia after low-dose methotrexate treatment for arthritis. The leukocyte count recovered after methotrexate was withdrawn but a leukemoid blood picture developed during her recovery. No evidence of leukemia was found on bone marrow biopsy. The leukocyte count gradually returned to normal with conservative therapy.

原文英語
頁(從 - 到)513-517
頁數5
期刊Chang Gung Medical Journal
29
發行號5
出版狀態已發佈 - 9月 2006
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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