Lens opacities in young individuals long after exposure to protracted low-dose-rate γ radiation in 60Co-contaminated buildings in Taiwan

Wanhua Annie Hsieh, I. Feng Lin, Wushou P. Chang, Wei Li Chen, Yea H. Hsu, Muh Shy Chen

研究成果: 雜誌貢獻文章

23 引文 (Scopus)

摘要

The objective of this study was to assess lenticular changes in a young population years after exposure to protracted long-term low-dose-rate γ radiation in Taiwan. A total of 41 males and 32 females who lived for several years in 60Co-contaminated buildings and were less than 20 years old at their first ophthalmological examination in 1998 had a similar examination 4.7 ± 0.5 years later. Lens opacities were examined by slit-lamp biomicroscopy and were scored by the Lens Opacities Classification System III (LOCS III) and a modified subclinical minor focal lens defect (FLD) system. The FLD scores for both eyes were significantly higher than those in the 1998 examinations. Increases in FLD scores compared to those for unexposed subjects occurred particularly in the anterior lens cortex. Increases in FLD scores were also significantly associated with the amount of previous protracted radiation exposure. An exposure-dependent increase in lens opacities was noted years after individuals relocated from the radiocontaminated environment, suggesting that late lenticular changes persisted and progressed in individuals with previous protracted radiation exposure.

原文英語
頁(從 - 到)197-204
頁數8
期刊Radiation Research
173
發行號2
DOIs
出版狀態已發佈 - 二月 2010

指紋

Taiwan
opacity
Cataract
Lenses
lenses
Radiation
dosage
radiation
examination
defects
radiation dosage
cortexes
luminaires
slits
Population
Radiation Exposure

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Biophysics
  • Radiation

引用此文

Lens opacities in young individuals long after exposure to protracted low-dose-rate γ radiation in 60Co-contaminated buildings in Taiwan. / Hsieh, Wanhua Annie; Lin, I. Feng; Chang, Wushou P.; Chen, Wei Li; Hsu, Yea H.; Chen, Muh Shy.

於: Radiation Research, 卷 173, 編號 2, 02.2010, p. 197-204.

研究成果: 雜誌貢獻文章

Hsieh, Wanhua Annie ; Lin, I. Feng ; Chang, Wushou P. ; Chen, Wei Li ; Hsu, Yea H. ; Chen, Muh Shy. / Lens opacities in young individuals long after exposure to protracted low-dose-rate γ radiation in 60Co-contaminated buildings in Taiwan. 於: Radiation Research. 2010 ; 卷 173, 編號 2. 頁 197-204.
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abstract = "The objective of this study was to assess lenticular changes in a young population years after exposure to protracted long-term low-dose-rate γ radiation in Taiwan. A total of 41 males and 32 females who lived for several years in 60Co-contaminated buildings and were less than 20 years old at their first ophthalmological examination in 1998 had a similar examination 4.7 ± 0.5 years later. Lens opacities were examined by slit-lamp biomicroscopy and were scored by the Lens Opacities Classification System III (LOCS III) and a modified subclinical minor focal lens defect (FLD) system. The FLD scores for both eyes were significantly higher than those in the 1998 examinations. Increases in FLD scores compared to those for unexposed subjects occurred particularly in the anterior lens cortex. Increases in FLD scores were also significantly associated with the amount of previous protracted radiation exposure. An exposure-dependent increase in lens opacities was noted years after individuals relocated from the radiocontaminated environment, suggesting that late lenticular changes persisted and progressed in individuals with previous protracted radiation exposure.",
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