Left atrial spontaneous echo contrast in patients with rheumatic mitral valve disease in sinus rhythm: Implication of an altered left atrial appendage function in its formation

Y. H. Li, J. J. Hwang, Y. L. Ko, J. L. Lin, Y. Z. Tseng, P. Kuan, W. P. Lien

研究成果: 雜誌貢獻文章

26 引文 (Scopus)

摘要

Thirty-nine patients who had rheumatic mitral valve disease in sinus rhythm were studied to compare echocardiographic and hemodynamic characteristics between those with and without left atrial (LA) spontaneous echo contrast. Patients were divided into two groups according to the presence (group 1, n=17) or absence (group 2, n=22) of the echo contrast. Transthoracic echocardiography and transesophageal echocardiography were performed in all patients within 1 week of cardiac catheterization study. Group I patients (5 men and 12 women; mean age, 47.7 ± 13.1 years) showed smaller mitral valve area, greater transmitral vane pressure gradient, and absence of moderate to severe mitral regurgitation compared with group 2 patients (7 men and 15 women; mean age, 47.8 ± 14.3 years). There was no significant difference in LA dimension, left ventricular end-systolic and end-diastolic dimensions, or in left ventricular ejection fraction between the two groups of patients. Left atrial appendage function was studied with Doppler in 26 patients. Patients (n=10) with LA spontaneous echo contrast had significantly lower LA appendage ejection fraction (20.34 ± 10.76% vs 34.16 ± 13.13%; p<0.05) and lower LA appendage peak emptying velocity (0.17 ± 0.09 m/s vs 0.27 ± 0.12 m/s; p<0.05) than those (n=16) without echo contrast. It is concluded that obstruction to mitral flow and altered LA appendage contractile function, not the LA size, are likely to be more important factors for the development of LA and LA appendage spontaneous echo contrast in patients with rheumatic mitral valve disease (predominant mitral stenosis) who are in sinus rhythm. These findings further substantiate that blood stasis in the LA cavity and the LA appendage is the mechanism fundamental to the formation of such spontaneous echo contrast.
原文英語
頁(從 - 到)99-103
頁數5
期刊Chest
108
發行號1
DOIs
出版狀態已發佈 - 一月 1 1995
對外發佈Yes

指紋

Left Atrial Function
Atrial Appendage
Mitral Valve
Mitral Valve Stenosis
Transesophageal Echocardiography
Mitral Valve Insufficiency
Cardiac Catheterization
Stroke Volume
Echocardiography
Hemodynamics

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

引用此文

Left atrial spontaneous echo contrast in patients with rheumatic mitral valve disease in sinus rhythm : Implication of an altered left atrial appendage function in its formation. / Li, Y. H.; Hwang, J. J.; Ko, Y. L.; Lin, J. L.; Tseng, Y. Z.; Kuan, P.; Lien, W. P.

於: Chest, 卷 108, 編號 1, 01.01.1995, p. 99-103.

研究成果: 雜誌貢獻文章

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title = "Left atrial spontaneous echo contrast in patients with rheumatic mitral valve disease in sinus rhythm: Implication of an altered left atrial appendage function in its formation",
abstract = "Thirty-nine patients who had rheumatic mitral valve disease in sinus rhythm were studied to compare echocardiographic and hemodynamic characteristics between those with and without left atrial (LA) spontaneous echo contrast. Patients were divided into two groups according to the presence (group 1, n=17) or absence (group 2, n=22) of the echo contrast. Transthoracic echocardiography and transesophageal echocardiography were performed in all patients within 1 week of cardiac catheterization study. Group I patients (5 men and 12 women; mean age, 47.7 ± 13.1 years) showed smaller mitral valve area, greater transmitral vane pressure gradient, and absence of moderate to severe mitral regurgitation compared with group 2 patients (7 men and 15 women; mean age, 47.8 ± 14.3 years). There was no significant difference in LA dimension, left ventricular end-systolic and end-diastolic dimensions, or in left ventricular ejection fraction between the two groups of patients. Left atrial appendage function was studied with Doppler in 26 patients. Patients (n=10) with LA spontaneous echo contrast had significantly lower LA appendage ejection fraction (20.34 ± 10.76{\%} vs 34.16 ± 13.13{\%}; p<0.05) and lower LA appendage peak emptying velocity (0.17 ± 0.09 m/s vs 0.27 ± 0.12 m/s; p<0.05) than those (n=16) without echo contrast. It is concluded that obstruction to mitral flow and altered LA appendage contractile function, not the LA size, are likely to be more important factors for the development of LA and LA appendage spontaneous echo contrast in patients with rheumatic mitral valve disease (predominant mitral stenosis) who are in sinus rhythm. These findings further substantiate that blood stasis in the LA cavity and the LA appendage is the mechanism fundamental to the formation of such spontaneous echo contrast.",
keywords = "left atrial appendage function, left atrial spontaneous echo contrast, rheumatic mitral valve disease, sinus rhythm, transesophageal echocardiography",
author = "Li, {Y. H.} and Hwang, {J. J.} and Ko, {Y. L.} and Lin, {J. L.} and Tseng, {Y. Z.} and P. Kuan and Lien, {W. P.}",
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T1 - Left atrial spontaneous echo contrast in patients with rheumatic mitral valve disease in sinus rhythm

T2 - Implication of an altered left atrial appendage function in its formation

AU - Li, Y. H.

AU - Hwang, J. J.

AU - Ko, Y. L.

AU - Lin, J. L.

AU - Tseng, Y. Z.

AU - Kuan, P.

AU - Lien, W. P.

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N2 - Thirty-nine patients who had rheumatic mitral valve disease in sinus rhythm were studied to compare echocardiographic and hemodynamic characteristics between those with and without left atrial (LA) spontaneous echo contrast. Patients were divided into two groups according to the presence (group 1, n=17) or absence (group 2, n=22) of the echo contrast. Transthoracic echocardiography and transesophageal echocardiography were performed in all patients within 1 week of cardiac catheterization study. Group I patients (5 men and 12 women; mean age, 47.7 ± 13.1 years) showed smaller mitral valve area, greater transmitral vane pressure gradient, and absence of moderate to severe mitral regurgitation compared with group 2 patients (7 men and 15 women; mean age, 47.8 ± 14.3 years). There was no significant difference in LA dimension, left ventricular end-systolic and end-diastolic dimensions, or in left ventricular ejection fraction between the two groups of patients. Left atrial appendage function was studied with Doppler in 26 patients. Patients (n=10) with LA spontaneous echo contrast had significantly lower LA appendage ejection fraction (20.34 ± 10.76% vs 34.16 ± 13.13%; p<0.05) and lower LA appendage peak emptying velocity (0.17 ± 0.09 m/s vs 0.27 ± 0.12 m/s; p<0.05) than those (n=16) without echo contrast. It is concluded that obstruction to mitral flow and altered LA appendage contractile function, not the LA size, are likely to be more important factors for the development of LA and LA appendage spontaneous echo contrast in patients with rheumatic mitral valve disease (predominant mitral stenosis) who are in sinus rhythm. These findings further substantiate that blood stasis in the LA cavity and the LA appendage is the mechanism fundamental to the formation of such spontaneous echo contrast.

AB - Thirty-nine patients who had rheumatic mitral valve disease in sinus rhythm were studied to compare echocardiographic and hemodynamic characteristics between those with and without left atrial (LA) spontaneous echo contrast. Patients were divided into two groups according to the presence (group 1, n=17) or absence (group 2, n=22) of the echo contrast. Transthoracic echocardiography and transesophageal echocardiography were performed in all patients within 1 week of cardiac catheterization study. Group I patients (5 men and 12 women; mean age, 47.7 ± 13.1 years) showed smaller mitral valve area, greater transmitral vane pressure gradient, and absence of moderate to severe mitral regurgitation compared with group 2 patients (7 men and 15 women; mean age, 47.8 ± 14.3 years). There was no significant difference in LA dimension, left ventricular end-systolic and end-diastolic dimensions, or in left ventricular ejection fraction between the two groups of patients. Left atrial appendage function was studied with Doppler in 26 patients. Patients (n=10) with LA spontaneous echo contrast had significantly lower LA appendage ejection fraction (20.34 ± 10.76% vs 34.16 ± 13.13%; p<0.05) and lower LA appendage peak emptying velocity (0.17 ± 0.09 m/s vs 0.27 ± 0.12 m/s; p<0.05) than those (n=16) without echo contrast. It is concluded that obstruction to mitral flow and altered LA appendage contractile function, not the LA size, are likely to be more important factors for the development of LA and LA appendage spontaneous echo contrast in patients with rheumatic mitral valve disease (predominant mitral stenosis) who are in sinus rhythm. These findings further substantiate that blood stasis in the LA cavity and the LA appendage is the mechanism fundamental to the formation of such spontaneous echo contrast.

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