Large-scale assessment of consistency in sleep stage scoring rules among multiple sleep centers using an interpretable machine learning algorithm

Gi Ren Liu, Ting Yu Lin, Hau Tieng Wu, Yuan Chung Sheu, Ching Lung Liu, Wen Te Liu, Mei Chen Yang, Yung Lun Ni, Kun Ta Chou, Chao Hsien Chen, Dean Wu, Chou Chin Lan, Kuo Liang Chiu, Hwa Yen Chiu, Yu Lun Lo

研究成果: 雜誌貢獻文章同行評審

摘要

Study Objectives: Polysomnography is the gold standard in identifying sleep stages; however, there are discrepancies in how technicians use the standards. Because organizing meetings to evaluate this discrepancy and/or reach a consensus among multiple sleep centers is time-consuming, we developed an artificial intelligence system to efficiently evaluate the reliability and consistency of sleep scoring and hence the sleep center quality. Methods: An interpretable machine learning algorithm was used to evaluate the interrater reliability (IRR) of sleep stage annotation among sleep centers. The artificial intelligence system was trained to learn raters from 1 hospital and was applied to patients from the same or other hospitals. The results were compared with the experts' annotation to determine IRR. Intracenter and intercenter assessments were conducted on 679 patients without sleep apnea from 6 sleep centers in Taiwan. Centers with potential quality issues were identified by the estimated IRR. Results: In the intracenter assessment, the median accuracy ranged from 80.3%-83.3%, with the exception of 1 hospital, which had an accuracy of 72.3%. In the intercenter assessment, the median accuracy ranged from 75.7%-83.3% when the 1 hospital was excluded from testing and training. The performance of the proposed method was higher for the N2, awake, and REMsleep stages than for the N1 and N3 stages. The significant IRR discrepancy of the 1 hospital suggested a quality issue. This quality issue was confirmed by the physicians in charge of the 1 hospital. Conclusions: The proposed artificial intelligence system proved effective in assessing IRR and hence the sleep center quality.
原文英語
頁(從 - 到)159-166
頁數8
期刊Journal of Clinical Sleep Medicine
17
發行號2
DOIs
出版狀態已發佈 - 二月 1 2021

ASJC Scopus subject areas

  • 肺和呼吸系統醫學
  • 神經內科
  • 神經病學(臨床)

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