Kinetic studies of the photochemical decomposition of alkannin/shikonin enantiomers

Fu An Chen, Hui Wen Cheng, An-Bang Wu, Hsing Chu Hsu, Chau Yang Chen

研究成果: 雜誌貢獻文章

15 引文 (Scopus)

摘要

The photodegradation of alkannin/shikonin (A/S) was studied as a function of solvent polarity, pH and ionic strength. This process follows an apparent first-order kinetic reaction. The photodegradation rate is inversely proportional to the solvent polarity in the order of chloroform > dichloromethane > 2-propanol > ethanol > methanol. The rate-pH profile reveals that A/S is more stable in an acidic condition: marginally subject to specific acid or base catalysis and is affected by two ionizable groups on the molecule. Ionic strength does not affect the photochemical decomposition rate at pH 5, 9 or 12.

原文英語
頁(從 - 到)249-251
頁數3
期刊Chemical and Pharmaceutical Bulletin
44
發行號1
出版狀態已發佈 - 一月 1996

指紋

Enantiomers
Photodegradation
Ionic strength
Photolysis
Decomposition
Osmolar Concentration
Kinetics
2-Propanol
Methylene Chloride
Chloroform
Reaction kinetics
Catalysis
Methanol
Ethanol
Molecules
Acids
alkannin
shikonin

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

引用此文

Kinetic studies of the photochemical decomposition of alkannin/shikonin enantiomers. / Chen, Fu An; Cheng, Hui Wen; Wu, An-Bang; Hsu, Hsing Chu; Chen, Chau Yang.

於: Chemical and Pharmaceutical Bulletin, 卷 44, 編號 1, 01.1996, p. 249-251.

研究成果: 雜誌貢獻文章

Chen, Fu An ; Cheng, Hui Wen ; Wu, An-Bang ; Hsu, Hsing Chu ; Chen, Chau Yang. / Kinetic studies of the photochemical decomposition of alkannin/shikonin enantiomers. 於: Chemical and Pharmaceutical Bulletin. 1996 ; 卷 44, 編號 1. 頁 249-251.
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