Isolation of Salmonella enterica serotype choleraesuis resistant to ceftriaxone and ciprofloxacin

C. H. Chiu, L. H. Su, C. Chu, J. H. Chia, T. L. Wu, T. Y. Lin, Y. S. Lee, J. T. Ou

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68 引文 斯高帕斯(Scopus)

摘要

Salmonella enterica serotype choleraesuis (S choleraesuis) usually causes systemic infections in man that need antimicrobial treatment. We isolated a strain of S choleraesuis that was resistant to ceftriaxone and ciprofloxacin from a patient with sepsis. Ciprofloxacin resistance was associated with mutations in gyrA and parC, whereas the ampC gene (blaCMY-2), responsible for ceftriaxone resistance, was carried by a transposon-like mobile element. This element was found inserted into finQ of a potentially transmissible 140 kb plasmid, with an 8 bp direct repeat flanking the junction regions. The appearance of this resistant S choleraesuis is a serious threat to public health, and thus constant surveillance is warranted.
原文英語
頁(從 - 到)1285-1286
頁數2
期刊Lancet
363
發行號9417
DOIs
出版狀態已發佈 - 四月 17 2004
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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