Isolation and identification of a novel spotted fever group rickettsia, strain IG-1, from Ixodes granulatus ticks collected on Orchid Island (Lanyu), Taiwan

Kun Hsien Tsai, Hsi Chieh Wang, Chun Hsien Chen, Jyh Hsiung Huang, Hsiu Ying Lu, Chien Ling Su, Pei Yun Shu

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)

摘要

A novel species of spotted fever group (SFG) rickettsia, Rickettsia spp. IG-1, was identified and isolated from adult Ixodes granulatus ticks collected from Orchid Island (Lanyu), an islet located in southeastern Taiwan. Serum samples collected from the rodent host Rattus losea and SFG-positive human serum reacted with IG-1 using an immunofluorescence assay (IFA). Pairwise nucleotide sequence analysis of 16S rRNA (rrs), gltA, ompA, ompB, and sca4 shows that IG-1 belongs to SFG rickettsiae and had the highest nucleotide sequence similarities to Rickettsia slovaca and R. sibirica. Phylogenetic analysis of the ompA, ompB genes and sca4 shows that IG-1 is most closely related to R. honei. The results showed the sequence divergence of this novel isolate from those rickettsiae previously characterized using the criteria proposed by Fournier and others. Whether IG-1 is pathogenic for humans remains to be studied.
原文英語
頁(從 - 到)256-261
頁數6
期刊American Journal of Tropical Medicine and Hygiene
79
發行號2
出版狀態已發佈 - 八月 1 2008
對外發佈Yes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

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