摘要
Purpose: Our purpose was to examine the timing of implantation and early embryo development following uterine transfer of oocytes/embryos previously subjected to zona pellucida micromanipulation. Methods: A total of 68 singleton pregnancies resulting from IVF and embryo transfer with/without micromanipulation. Patients were divided into four groups according to the type of micromanipulation technique: assisted hatching, embryo biopsy, intracytoplasmic sperm injection, and no micromanipulation (control group). Serial serum β-hCG levels were measured between 10 and 25 days after fertilization and log-transformed. Linear regression analyses were performed and extrapolated to hCG = 10 mlU/ml (hCG10) to estimate detectable implantation. The slopes of the regression lines were used to estimate the rising speed of hCG, an indirect sign of embryo development. Results: There were no significant differences among groups with respect to hCG10, the slopes or intercepts of the regression lines. Conclusions: Various oocyte/embryo microsurgical procedures used in ART involving zona pellucida manipulation do not appear to affect the timing of implantation or early embryo development.
原文 | 英語 |
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頁(從 - 到) | 34-38 |
頁數 | 5 |
期刊 | Journal of Assisted Reproduction and Genetics |
卷 | 17 |
發行號 | 1 |
DOIs | |
出版狀態 | 已發佈 - 2000 |
對外發佈 | 是 |
ASJC Scopus subject areas
- 婦產科
- 發展生物學
- 遺傳學
- 生殖醫學