Is the timing of implantation affected by Zona pellucida micromanipulation?

Ming I. Hsu, Gerardo Barroso, Jacob Mayer, Susan Lanzendorf, William E. Gibbons, Suheil Muasher, Sergio Oehninger

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

摘要

Purpose: Our purpose was to examine the timing of implantation and early embryo development following uterine transfer of oocytes/embryos previously subjected to zona pellucida micromanipulation. Methods: A total of 68 singleton pregnancies resulting from IVF and embryo transfer with/without micromanipulation. Patients were divided into four groups according to the type of micromanipulation technique: assisted hatching, embryo biopsy, intracytoplasmic sperm injection, and no micromanipulation (control group). Serial serum β-hCG levels were measured between 10 and 25 days after fertilization and log-transformed. Linear regression analyses were performed and extrapolated to hCG = 10 mlU/ml (hCG10) to estimate detectable implantation. The slopes of the regression lines were used to estimate the rising speed of hCG, an indirect sign of embryo development. Results: There were no significant differences among groups with respect to hCG10, the slopes or intercepts of the regression lines. Conclusions: Various oocyte/embryo microsurgical procedures used in ART involving zona pellucida manipulation do not appear to affect the timing of implantation or early embryo development.

原文英語
頁(從 - 到)34-38
頁數5
期刊Journal of Assisted Reproduction and Genetics
17
發行號1
DOIs
出版狀態已發佈 - 2000
對外發佈Yes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Developmental Biology
  • Genetics
  • Reproductive Medicine

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