Is the sense of agency in schizophrenia influenced by resting-state variation in self-referential regions of the brain?

Jeffrey D. Robinson, Nils Frederic Wagner, Georg Northoff

研究成果: 雜誌貢獻文章同行評審

19 引文 斯高帕斯(Scopus)

摘要

Schizophrenia is a disturbance of the self, of which the attribution of agency is a major component. In this article, we review current theories of the Sense of Agency, their relevance to schizophrenia, and propose a novel framework for future research. We explore some of the models of agency, in which both bottom-up and top-down processes are implicated in the genesis of agency. We further this line of inquiry by suggesting that ongoing neurological activity (the brain's resting state) in self-referential regions of the brain can provide a deeper level of influence beyond what the current models capture. Based on neuroimaging studies, we suggest that aberrant activity in regions such as the default mode network of individuals with schizophrenia can lead to a misattribution of internally/externally generated stimuli. This can result in symptoms such as thought insertion and delusions of control. Consequently, neuroimaging can contribute to a more comprehensive conceptualization and measurement of agency and potential treatment implications.

原文英語
頁(從 - 到)270-276
頁數7
期刊Schizophrenia Bulletin
42
發行號2
DOIs
出版狀態已發佈 - 2016

ASJC Scopus subject areas

  • 精神病學和心理健康

指紋

深入研究「Is the sense of agency in schizophrenia influenced by resting-state variation in self-referential regions of the brain?」主題。共同形成了獨特的指紋。

引用此