Investigation of subcortical gray matter in patients with non-lesional neocortical focal epilepsy

Ying Chi Fan, Syu Jyun Peng, Tomor Harnod, Chien Chun Huang, Yue Loong Hsin

研究成果: 雜誌貢獻文章

摘要

Purpose: To investigate whether there is any change in the subcortical gray matter of patients with neocortical focal epilepsy without visible magnetic resonance imaging (MRI) abnormalities. Methods: MRI morphometric parameter data from 24 patients and 29 neurologically normal controls were analyzed. All of the MRI scans were reported to have no any anomaly. Differences were evaluated by vertex-wise shape analysis. Results: A shape analysis showed significant surface reductions at the anterior-ventral and the posteriordorsal aspects of the bilateral thalami, the global left caudate nucleus, part of the bilateral dorsal putamen and the left hippocampus. Conclusion: Patients with focal seizures and secondary generalization had smaller volumes and microstructural anomalies in subcortical gray matter regions.
原文英語
頁(從 - 到)124-128
頁數5
期刊Acta Neurologica Taiwanica
23
發行號4
出版狀態已發佈 - 一月 1 2014
對外發佈Yes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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