Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease

Ho Chang Kuo, Yu Wen Hsu, Mei Shin Wu, Shu-Chen Chien, Shih Feng Liu, Wei Chiao Chang

研究成果: 雜誌貢獻文章同行評審

21 引文 斯高帕斯(Scopus)

摘要

Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and it is therefore worth examining the multifactorial interaction of genes and environmental factors. Targeted genetic association and genome-wide association studies have helped to provide a better understanding of KD from infection to the immune-related response. Findings in the past decade have contributed to a major breakthrough in the genetics of KD, with the identification of several genomic regions linked to the pathogenesis of KD, including ITPKC, CD40, BLK, and FCGR2A. This review focuses on the factors associated with the genetic polymorphisms of KD and the pharmacogenomics of the response to treatment in patients with intravenous immunoglobulin resistance.

原文英語
頁(從 - 到)1-7
頁數7
期刊Journal of Microbiology, Immunology and Infection
49
發行號1
DOIs
出版狀態已發佈 - 二月 1 2016

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Infectious Diseases

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