Interleukin 10 and clustering of metabolic syndrome components in pediatrics

Jung Su Chang, Chyi Huey Bai, Zu Chieh Huang, Eddy Owaga, Kuo Ching Chao, Chun Chao Chang, Hung Yi Chiou

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

摘要

Background: Interleukin 10 (IL-10) has multifaceted anti-inflammatory properties that are known to regulate insulin sensitivity and atherosclerotic development. However, studies in children are limited and have yielded conflicting results. The aim of this study was to evaluate whether changes in this circulating anti-inflammatory cytokine is a marker for metabolic syndrome. Materials and methods: This cross-sectional study involved children and young adolescents from eight elementary schools and two junior high schools located in Taipei and New Taipei City. A total of 553 children ages 8, 11 and 13 years old were included in the analysis. Parameters for obesity, anti- and pro-inflammatory cytokines, and metabolic risk profiles were evaluated. Results: Overweight/obese children had lower serum IL-10 concentrations compared with normal weight children in the same age group (all P 

原文英語
頁(從 - 到)384-394
頁數11
期刊European Journal of Clinical Investigation
44
發行號4
DOIs
出版狀態已發佈 - 2014

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Biochemistry
  • Biochemistry

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