Insulin-directed synthesis of fluorescent gold nanoclusters: Preservation of insulin bioactivity and versatility in cell imaging

Chien Liang Liu, Hung Tsung Wu, Yi Hsuan Hsiao, Chih Wei Lai, Chun Wei Shih, Yung Kang Peng, Kuo Chun Tang, Hsing Wei Chang, Yun Chen Chien, Jong Kai Hsiao, Juei Tang Cheng, Pi Tai Chou

研究成果: 雜誌貢獻文章

296 引文 (Scopus)

摘要

Go for gold: As-prepared insulin-Au nanoclusters (NCs) show intense red fluorescence, excellent biocompatibility, and preservation of natural insulin bioactivity in lowering the blood-glucose level. Their versatility in applications is demonstrated by fluorescence imaging, X-ray computed tomography, and insulin-inhibitor interactions (see picture; IDE=insulin-degrading enzyme).
原文英語
頁(從 - 到)7056-7060
頁數5
期刊Angewandte Chemie - International Edition
50
發行號31
DOIs
出版狀態已發佈 - 七月 25 2011
對外發佈Yes

指紋

Nanoclusters
Insulin
Bioactivity
Gold
Imaging techniques
Insulysin
Fluorescence
Biocompatibility
Tomography
Blood Glucose
Glucose
X rays
Blood
Enzymes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

引用此文

Insulin-directed synthesis of fluorescent gold nanoclusters : Preservation of insulin bioactivity and versatility in cell imaging. / Liu, Chien Liang; Wu, Hung Tsung; Hsiao, Yi Hsuan; Lai, Chih Wei; Shih, Chun Wei; Peng, Yung Kang; Tang, Kuo Chun; Chang, Hsing Wei; Chien, Yun Chen; Hsiao, Jong Kai; Cheng, Juei Tang; Chou, Pi Tai.

於: Angewandte Chemie - International Edition, 卷 50, 編號 31, 25.07.2011, p. 7056-7060.

研究成果: 雜誌貢獻文章

Liu, CL, Wu, HT, Hsiao, YH, Lai, CW, Shih, CW, Peng, YK, Tang, KC, Chang, HW, Chien, YC, Hsiao, JK, Cheng, JT & Chou, PT 2011, 'Insulin-directed synthesis of fluorescent gold nanoclusters: Preservation of insulin bioactivity and versatility in cell imaging', Angewandte Chemie - International Edition, 卷 50, 編號 31, 頁 7056-7060. https://doi.org/10.1002/anie.201100299
Liu, Chien Liang ; Wu, Hung Tsung ; Hsiao, Yi Hsuan ; Lai, Chih Wei ; Shih, Chun Wei ; Peng, Yung Kang ; Tang, Kuo Chun ; Chang, Hsing Wei ; Chien, Yun Chen ; Hsiao, Jong Kai ; Cheng, Juei Tang ; Chou, Pi Tai. / Insulin-directed synthesis of fluorescent gold nanoclusters : Preservation of insulin bioactivity and versatility in cell imaging. 於: Angewandte Chemie - International Edition. 2011 ; 卷 50, 編號 31. 頁 7056-7060.
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