Insulin-directed synthesis of fluorescent gold nanoclusters: Preservation of insulin bioactivity and versatility in cell imaging

Chien Liang Liu, Hung Tsung Wu, Yi Hsuan Hsiao, Chih Wei Lai, Chun Wei Shih, Yung Kang Peng, Kuo Chun Tang, Hsing Wei Chang, Yun Chen Chien, Jong Kai Hsiao, Juei Tang Cheng, Pi Tai Chou

研究成果: 雜誌貢獻文章

311 引文 斯高帕斯(Scopus)

摘要

Go for gold: As-prepared insulin-Au nanoclusters (NCs) show intense red fluorescence, excellent biocompatibility, and preservation of natural insulin bioactivity in lowering the blood-glucose level. Their versatility in applications is demonstrated by fluorescence imaging, X-ray computed tomography, and insulin-inhibitor interactions (see picture; IDE=insulin-degrading enzyme).
原文英語
頁(從 - 到)7056-7060
頁數5
期刊Angewandte Chemie - International Edition
50
發行號31
DOIs
出版狀態已發佈 - 七月 25 2011
對外發佈Yes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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    Liu, C. L., Wu, H. T., Hsiao, Y. H., Lai, C. W., Shih, C. W., Peng, Y. K., Tang, K. C., Chang, H. W., Chien, Y. C., Hsiao, J. K., Cheng, J. T., & Chou, P. T. (2011). Insulin-directed synthesis of fluorescent gold nanoclusters: Preservation of insulin bioactivity and versatility in cell imaging. Angewandte Chemie - International Edition, 50(31), 7056-7060. https://doi.org/10.1002/anie.201100299