Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013)

Hsueh Yun Lee, Chia-Ron Yang, Mei-Jung Lai, Han-Li Huang, Yi-Ling Hsieh, Yi-Min Liu, Teng-Kuang Yeh, Yu-Hsuan Li, Samir Mehndiratta, Che-Ming Teng, Jing Ping Liou

研究成果: 雜誌貢獻文章

摘要

The inside cover picture shows a SAR study of synthetic N-hydroxyacrylamides, described by J.-P. Liou et al. on p. 1248 ff., that identified 3-[1- (4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-5-yl]-N-hydroxyacrylamide as a potent HDAC inhibitor. This compound not only suppresses the production of lipopolysaccharide-induced cytokines but also markedly reduces carrageenan-induced inflammation in rat. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
原文英語
頁(從 - 到)1150
頁數1
期刊ChemBioChem
14
發行號10
DOIs
出版狀態已發佈 - 七月 2013

指紋

Histone Deacetylase Inhibitors
Carrageenan
Lipopolysaccharides
Rats
Cytokines
Inflammation
indoline
3-(1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide

Keywords

  • Anti-inflammatory agents
  • Gene expression
  • Histone deacetylase
  • Indolines
  • Inhibitors

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Molecular Medicine
  • Molecular Biology

引用此文

Inside Cover : 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013). / Lee, Hsueh Yun; Yang, Chia-Ron; Lai, Mei-Jung; Huang, Han-Li; Hsieh, Yi-Ling; Liu, Yi-Min; Yeh, Teng-Kuang; Li, Yu-Hsuan; Mehndiratta, Samir; Teng, Che-Ming; Liou, Jing Ping.

於: ChemBioChem, 卷 14, 編號 10, 07.2013, p. 1150.

研究成果: 雜誌貢獻文章

Lee, Hsueh Yun ; Yang, Chia-Ron ; Lai, Mei-Jung ; Huang, Han-Li ; Hsieh, Yi-Ling ; Liu, Yi-Min ; Yeh, Teng-Kuang ; Li, Yu-Hsuan ; Mehndiratta, Samir ; Teng, Che-Ming ; Liou, Jing Ping. / Inside Cover : 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013). 於: ChemBioChem. 2013 ; 卷 14, 編號 10. 頁 1150.
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