Influence of a static magnetic field on the slow freezing of human erythrocytes

Chun Yen Lin, Wei Jen Chang, Sheng Yang Lee, Sheng-Wei Feng, Che Tong Lin, Kan Shin Fan, Haw Ming Huang

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

Purpose: The aim of this study was to test whether or not a strong static magnetic field (SMF) had a positive effect on the survival rate of frozen erythrocytes. Materials and methods: Human erythrocytes were slow freezing at a rate of -1°C/min, to a final temperature of -20°C. During the freezing process, the cells were simultaneously exposed to an SMF with a magnetic induction of 0.2 or 0.4 T. After the cells were thawed, the survival rate, morphology, and function of the thawed erythrocytes were evaluated. Furthermore, tests of membrane fluidity were performed to assess the effect of the SMF on the cell membrane. Results: The slow freezing process coupled with an SMF increased the survival rate of frozen erythrocytes, without any negative effect on the cell morphology or function. The increases in relative survival rates of frozen erythrocytes were 5.7% and 9.1% when the cells were frozen in 0.2 T and 0.4 T groups, respectively. In addition, the 0.4 T group significantly increased the membrane rigidity of the erythrocytes. Conclusions: Slow freezing coupled with a strong SMF produced positive effects on the survival rate of thawed erythrocytes, without changing their normal function.
原文英語
頁(從 - 到)51-56
頁數6
期刊International Journal of Radiation Biology
89
發行號1
DOIs
出版狀態已發佈 - 一月 2013

ASJC Scopus subject areas

  • 放射學、核子醫學和影像學
  • 放射與超音波技術

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