Infectivity and pathogenicity of 14-month-cultured embryonated eggs of Toxocara canis in mice

Chia Kwung Fan, Yun Ho Lin, Wen Yuan Du, Kua Eyre Su

研究成果: 雜誌貢獻文章同行評審

43 引文 斯高帕斯(Scopus)

摘要

Infectivity and pathogenicity to mice of embryonated eggs of Toxocara canis, that had been maintained in 2% formalin for 14 months at 4°C, were evaluated by immunological and pathological assessment at 1, 4, 8, 12, 16, 20, 24, 28, 42 and 67 weeks post-infection (WPI). On each date, three infected mice and two age-matched uninfected mice were sacrificed for serum collection and histological processing of the liver, lungs, musculature, and brain. Infectivity assessment by enzyme-linked immunosorbent assay (ELISA) revealed that the overall immunological pattern of infected mice tended to be towards the Th2 type response. Serum IgG1 antibody titers in infected mice were significantly higher than that of the uninfected control mice throughout the trial (P
原文英語
頁(從 - 到)145-155
頁數11
期刊Veterinary Parasitology
113
發行號2
DOIs
出版狀態已發佈 - 四月 18 2003

ASJC Scopus subject areas

  • 寄生物學
  • 獸醫 (全部)

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