Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21

Yu Fang Kuang, Yue-Hwa Chen

研究成果: 雜誌貢獻文章

59 引文 斯高帕斯(Scopus)

摘要

This study was aimed at examining the effects of glucosinolate derivatives including phenylethyl isothiocyanate (PEITC), benzyl isothiocyanate (BITC), and indole-3-carbinol (I3C), on the induction of apoptosis in human non-small cell lung carcinoma A549 cells. The results indicated that all tested compounds inhibited the growth of A549 cells in a concentration-dependent manner. Flow cytometric analyses and annexin V staining showed that induction of apoptosis occurred at low concentrations of PEITC and BITC (â
原文英語
頁(從 - 到)1711-1718
頁數8
期刊Food and Chemical Toxicology
42
發行號10
DOIs
出版狀態已發佈 - 十月 2004

ASJC Scopus subject areas

  • Food Science
  • Toxicology

指紋 深入研究「Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21」主題。共同形成了獨特的指紋。

引用此