Indigenous Wildlife Rabies in Taiwan: Ferret Badgers, a Long Term Terrestrial Reservoir

Yu Ching Lan, Tzai Hung Wen, Chao Chin Chang, Hsin Fu Liu, Pei Fen Lee, Chung Yuan Huang, Bruno B. Chomel, Yi Ming A. Chen

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

摘要

The emerging disease of rabies was confirmed in Taiwan ferret badgers (FBs) and reported to the World Organization for Animal Health (OIE) on July 17, 2013. The spread of wildlife rabies can be related to neighborhood countries in Asia. The phylogenetic analysis was conducted by maximum likelihood (ML) methods and the Bayesian coalescent approach based on the glycoprotein (G) and nucleoprotein (N) genes. The phylogeographic and spatial temporal dynamics of viral transmission were determined by using SPREAD, QGIS. Therefore, the origin and the change with time of the viruses can be identified. Results showed the rabies virus of FB strains in Taiwan is a unique clade among other strains in Asia. According to the phylogeographic coalescent tree, three major genotypes of the FB rabies virus have circulated in three different geographical areas in Taiwan. Two genotypes have distributed into central and southern Taiwan between two ecological river barriers. The third genotype has been limited in southeastern Taiwan by the natural mountain barrier. The diversity of FB rabies viruses indicates that the biological profile of FBs could vary in different geographical areas in Taiwan. An enhanced surveillance system needs to be established near the currently identified natural barriers for early warnings of the rabies virus outbreak in Taiwan.
原文英語
文章編號5491640
期刊BioMed Research International
2017
DOIs
出版狀態已發佈 - 一月 1 2017
對外發佈Yes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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    Lan, Y. C., Wen, T. H., Chang, C. C., Liu, H. F., Lee, P. F., Huang, C. Y., Chomel, B. B., & Chen, Y. M. A. (2017). Indigenous Wildlife Rabies in Taiwan: Ferret Badgers, a Long Term Terrestrial Reservoir. BioMed Research International, 2017, [5491640]. https://doi.org/10.1155/2017/5491640