Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

Cheng Hsun Chiu, Lin Hui Su, Yhu Chering Huang, Jui Chia Lai, Hsiu Ling Chen, Tsu Lan Wu, Tzou Yien Lin

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)

摘要

The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.
原文英語
頁(從 - 到)3404-3406
頁數3
期刊Antimicrobial Agents and Chemotherapy
51
發行號9
DOIs
出版狀態已發佈 - 九月 2007
對外發佈Yes

    指紋

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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