Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

Cheng Hsun Chiu, Lin Hui Su, Yhu Chering Huang, Jui Chia Lai, Hsiu Ling Chen, Tsu Lan Wu, Tzou Yien Lin

研究成果: 雜誌貢獻文章

24 引文 (Scopus)

摘要

The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.
原文英語
頁(從 - 到)3404-3406
頁數3
期刊Antimicrobial Agents and Chemotherapy
51
發行號9
DOIs
出版狀態已發佈 - 九月 2007
對外發佈Yes

指紋

Penicillin-Binding Proteins
Ceftriaxone
Streptococcus pneumoniae
Taiwan
Penicillins
Peptidyl Transferases
Amino Acids
Serogroup

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

引用此文

Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan. / Chiu, Cheng Hsun; Su, Lin Hui; Huang, Yhu Chering; Lai, Jui Chia; Chen, Hsiu Ling; Wu, Tsu Lan; Lin, Tzou Yien.

於: Antimicrobial Agents and Chemotherapy, 卷 51, 編號 9, 09.2007, p. 3404-3406.

研究成果: 雜誌貢獻文章

Chiu, Cheng Hsun ; Su, Lin Hui ; Huang, Yhu Chering ; Lai, Jui Chia ; Chen, Hsiu Ling ; Wu, Tsu Lan ; Lin, Tzou Yien. / Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan. 於: Antimicrobial Agents and Chemotherapy. 2007 ; 卷 51, 編號 9. 頁 3404-3406.
@article{b98db303fa5244d4ae052643ddb9865d,
title = "Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan",
abstract = "The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90{\%} of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.",
author = "Chiu, {Cheng Hsun} and Su, {Lin Hui} and Huang, {Yhu Chering} and Lai, {Jui Chia} and Chen, {Hsiu Ling} and Wu, {Tsu Lan} and Lin, {Tzou Yien}",
year = "2007",
month = "9",
doi = "10.1128/AAC.01563-06",
language = "English",
volume = "51",
pages = "3404--3406",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "9",

}

TY - JOUR

T1 - Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan

AU - Chiu, Cheng Hsun

AU - Su, Lin Hui

AU - Huang, Yhu Chering

AU - Lai, Jui Chia

AU - Chen, Hsiu Ling

AU - Wu, Tsu Lan

AU - Lin, Tzou Yien

PY - 2007/9

Y1 - 2007/9

N2 - The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

AB - The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

UR - http://www.scopus.com/inward/record.url?scp=35948975073&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35948975073&partnerID=8YFLogxK

U2 - 10.1128/AAC.01563-06

DO - 10.1128/AAC.01563-06

M3 - Article

C2 - 17591850

AN - SCOPUS:35948975073

VL - 51

SP - 3404

EP - 3406

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 9

ER -