Increased dietary zinc and vitamin B-2 is associated with increased alanine aminotransferase in Taiwanese adolescents

Chyi-Huey Bai, Yi-Wen Chien, Tzu chieh Huang, Shin Jiuan Wu, Nai Hua Yeh, Harn Wen Pan, Jung-Su Chang

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

Background and Objectives: Alanine aminotransferase (ALT) is generally used for evaluating liver function, and its concentrations are closely associated with sex and nutritional status. This study investigates the relationships between dietary components and serum ALT activity in Taiwanese adolescents. Methods and Study Design: Data were collected from 1,941 adolescents aged 13-18 years who participated in the fourth National Nutrition and Health Survey in Taiwan (2010-2011, adolescents). Results: The mean age was 15.3±0.1 y (15.3±0.1 y for boys and 15.2±0.1 y for girls). Mean serum ALT was 14.8±13.3 U/L (17.7±16.3 U/L for boys and 12.1±8.7 U/L for girls; p < 0.001). Multivariate analysis revealed that, among girls, a single-unit increase in dietary zinc was associated with 1.12- and 1.11-fold increases in risk for increased serum ALT tertile 2 (T2) and T3, respectively, compared with T1; and a single-unit increase in vitamin B-2 intake increased risk by 1.71- and 1.54-fold, respectively. Further analysis revealed that the risk increase for boys and girls who consumed the highest amounts of dietary zinc and vitamin B-2 (T3) was 1.97- and 2.62-fold, respectively; they were also more likely to have higher serum ALT (> 11 U/L for boys and > 9 U/L for girls) than those of the reference (presented as zinc T1 and vitamin B-1 T1). Conclusions: Increased dietary zinc and vitamin B-2 intake is associated with higher serum ALT in adolescents.
原文英語
頁(從 - 到)78-84
頁數7
期刊Asia Pacific Journal of Clinical Nutrition
26
發行號1
DOIs
出版狀態已發佈 - 2017

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Medicine(all)
  • Nutrition and Dietetics

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