Increased corrosion resistance of stent materials by converting current surface film of polycrystalline oxide into amorphous oxide

Chun Che Shih, Shing Jong Lin, Kwok Hung Chung, Yuh Lien Chen, Yea Yang Su

研究成果: 雜誌貢獻文章同行評審

96 引文 斯高帕斯(Scopus)

摘要

Current efforts of new stent technology have been aimed largely at the improvement of intravascular stent biocompatibility. Among the chemical characteristics of metallic stents, surface oxide corrosion properties are paramount. Using our unique technique, the currently marketed 316 L stainless steel and nitinol stent wires covered with polycrystalline oxide were chemically etched and then passivated to form amorphous oxide. Excellent metallicstent corrosion resistance with an amorphous oxide surface was demonstrated in our previous in vitro study. For in viva validation, we compared the corrosion behavior of different oxide surfaces on various forms of test wires in the abdominal aorta of mongrel dogs using open-circuit potential and cyclic anodic polarization measurements. After conduction, the retrieved test wires were observed under scanning electron microscope. No passivity breakdown was found for wires covered with amorphous oxide, while wires with polycrystalline oxide showed breakdown at potentials between +0.2 to + 0.6 V. It has been proven that severe pitting or crevice corrosion occurred on the surface of polycrystalline oxide, while the surface of amorphous oxide was free of degradations in our experiment. We have dermostrated that this amorphous oxide coating on metallic material provides better corrosion resistance, not only in vitro but also in vivo, and it is superior not only in strength safety but also in medical device biocompatibility. (C) 2000 John Wiley and Sons, Inc.
原文英語
頁(從 - 到)323-332
頁數10
期刊Journal of Biomedical Materials Research
52
發行號2
DOIs
出版狀態已發佈 - 一月 1 2000
對外發佈Yes

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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