In vivo graft performance of an improved bone substitute composed of poor crystalline hydroxyapatite based biphasic calcium phosphate

Ching Lien Hung, Jen Chang Yang, Wei Jen Chang, Chih Yuan Hu, Yong Ho Lin, Chun Hsien Huang, Chien Chung Chen, Sheng Yang Lee, Nai Chia Teng

研究成果: 雜誌貢獻文章同行評審

10 引文 斯高帕斯(Scopus)

摘要

The ability to promote new bone formation of poor crystalline hydroxyapatite (PC-HA) based biphasic calcium phosphate (BCP) bone substitutes were investigated. Various ratios of porous PC-HA/β-TCP (70/30, 60/40, and 0/100) grafts were fabricated. SEM and XRD measurements were performed to study the morphology and crystalline structure. Cylindrical artificial bone defects (3×6 mm2) were produced in alveolar bone at premolars extraction site and then filled with sterilized bone grafts. Commercial MBCP® and unfilled empty defect served as control groups. At 8 weeks postoperation, samples were harvested from each artificial defect site for histological analysis. New bone formation of all the PC-HA/β-TCP groups was significantly greater than that of the empty control group (p
原文英語
頁(從 - 到)21-28
頁數8
期刊Dental Materials Journal
30
發行號1
DOIs
出版狀態已發佈 - 2011

ASJC Scopus subject areas

  • Dentistry(all)
  • Ceramics and Composites

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