In-car particles and cardiovascular health: An air conditioning-based intervention study

Hsiao Chi Chuang, Lian Yu Lin, Ya Wen Hsu, Chih Ming Ma, Kai Jen Chuang

研究成果: 雜誌貢獻文章

12 引文 (Scopus)

摘要

Exposure to traffic-related particulate matter (PM) is considered a potential risk for cardiovascular events. Little is known about whether improving air quality in car can modify cardiovascular effects among human subjects during commuting. We recruited a panel of 60 healthy subjects to commute for 2h by a car equipped with an air conditioning (AC) system during the morning rush hour in Taipei. Operation modes of AC system using outside air (OA-mode), circulating inside air (IA-mode) and turning off (Off-mode) were examined. Repeated measurements of heart rate variability (HRV) indices, PM≤2.5μm in aerodynamic diameter (PM2.5) and noise level were conducted for each participant in different modes during the commute. We used linear mixed-effects models to associate HRV indices with in-car PM2.5. We found that decreases in HRV indices were associated with increased levels of in-car PM2.5. For Off-mode, an interquartile range (IQR) increase in in-car PM2.5 with 15-min moving average was associated with 2.7% and 4.1% decreases in standard deviation of NN intervals (SDNN) and the square root of the mean of the sum of the squares of differences between adjacent NN intervals (r-MSSD), respectively. During OA and IA modes, participants showed slight decreases in SDNN (OA mode: 0.1%; IA mode: 1.3%) and r-MSSD (OA mode: 1.1%; IA mode: 1.8%) by an IQR increase in in-car PM2.5 with 15-min moving average. We concluded that in-car PM2.5 is associated with autonomic alteration. Utilization of the car's AC system can improve air quality and modify the effects of in-car PM2.5 on HRV indices among human subjects during the commute.

原文英語
頁(從 - 到)309-313
頁數5
期刊Science of the Total Environment
452-453
DOIs
出版狀態已發佈 - 五月 1 2013

指紋

Air Conditioning
air conditioning
Air conditioning
automobile
Railroad cars
Heart Rate
Air
Health
Particulate Matter
Noise
Air quality
Healthy Volunteers
air quality
health
particle
commuting
air
aerodynamics
particulate matter
Aerodynamics

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Waste Management and Disposal
  • Environmental Engineering
  • Medicine(all)

引用此文

In-car particles and cardiovascular health : An air conditioning-based intervention study. / Chuang, Hsiao Chi; Lin, Lian Yu; Hsu, Ya Wen; Ma, Chih Ming; Chuang, Kai Jen.

於: Science of the Total Environment, 卷 452-453, 01.05.2013, p. 309-313.

研究成果: 雜誌貢獻文章

@article{b2dd445c676a41ca80f87ee4fcb582f3,
title = "In-car particles and cardiovascular health: An air conditioning-based intervention study",
abstract = "Exposure to traffic-related particulate matter (PM) is considered a potential risk for cardiovascular events. Little is known about whether improving air quality in car can modify cardiovascular effects among human subjects during commuting. We recruited a panel of 60 healthy subjects to commute for 2h by a car equipped with an air conditioning (AC) system during the morning rush hour in Taipei. Operation modes of AC system using outside air (OA-mode), circulating inside air (IA-mode) and turning off (Off-mode) were examined. Repeated measurements of heart rate variability (HRV) indices, PM≤2.5μm in aerodynamic diameter (PM2.5) and noise level were conducted for each participant in different modes during the commute. We used linear mixed-effects models to associate HRV indices with in-car PM2.5. We found that decreases in HRV indices were associated with increased levels of in-car PM2.5. For Off-mode, an interquartile range (IQR) increase in in-car PM2.5 with 15-min moving average was associated with 2.7{\%} and 4.1{\%} decreases in standard deviation of NN intervals (SDNN) and the square root of the mean of the sum of the squares of differences between adjacent NN intervals (r-MSSD), respectively. During OA and IA modes, participants showed slight decreases in SDNN (OA mode: 0.1{\%}; IA mode: 1.3{\%}) and r-MSSD (OA mode: 1.1{\%}; IA mode: 1.8{\%}) by an IQR increase in in-car PM2.5 with 15-min moving average. We concluded that in-car PM2.5 is associated with autonomic alteration. Utilization of the car's AC system can improve air quality and modify the effects of in-car PM2.5 on HRV indices among human subjects during the commute.",
keywords = "Air conditioning system, Car, Epidemiology, Heart rate variability, Indoor air pollution, Particulate matter",
author = "Chuang, {Hsiao Chi} and Lin, {Lian Yu} and Hsu, {Ya Wen} and Ma, {Chih Ming} and Chuang, {Kai Jen}",
year = "2013",
month = "5",
day = "1",
doi = "10.1016/j.scitotenv.2013.02.097",
language = "English",
volume = "452-453",
pages = "309--313",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier",

}

TY - JOUR

T1 - In-car particles and cardiovascular health

T2 - An air conditioning-based intervention study

AU - Chuang, Hsiao Chi

AU - Lin, Lian Yu

AU - Hsu, Ya Wen

AU - Ma, Chih Ming

AU - Chuang, Kai Jen

PY - 2013/5/1

Y1 - 2013/5/1

N2 - Exposure to traffic-related particulate matter (PM) is considered a potential risk for cardiovascular events. Little is known about whether improving air quality in car can modify cardiovascular effects among human subjects during commuting. We recruited a panel of 60 healthy subjects to commute for 2h by a car equipped with an air conditioning (AC) system during the morning rush hour in Taipei. Operation modes of AC system using outside air (OA-mode), circulating inside air (IA-mode) and turning off (Off-mode) were examined. Repeated measurements of heart rate variability (HRV) indices, PM≤2.5μm in aerodynamic diameter (PM2.5) and noise level were conducted for each participant in different modes during the commute. We used linear mixed-effects models to associate HRV indices with in-car PM2.5. We found that decreases in HRV indices were associated with increased levels of in-car PM2.5. For Off-mode, an interquartile range (IQR) increase in in-car PM2.5 with 15-min moving average was associated with 2.7% and 4.1% decreases in standard deviation of NN intervals (SDNN) and the square root of the mean of the sum of the squares of differences between adjacent NN intervals (r-MSSD), respectively. During OA and IA modes, participants showed slight decreases in SDNN (OA mode: 0.1%; IA mode: 1.3%) and r-MSSD (OA mode: 1.1%; IA mode: 1.8%) by an IQR increase in in-car PM2.5 with 15-min moving average. We concluded that in-car PM2.5 is associated with autonomic alteration. Utilization of the car's AC system can improve air quality and modify the effects of in-car PM2.5 on HRV indices among human subjects during the commute.

AB - Exposure to traffic-related particulate matter (PM) is considered a potential risk for cardiovascular events. Little is known about whether improving air quality in car can modify cardiovascular effects among human subjects during commuting. We recruited a panel of 60 healthy subjects to commute for 2h by a car equipped with an air conditioning (AC) system during the morning rush hour in Taipei. Operation modes of AC system using outside air (OA-mode), circulating inside air (IA-mode) and turning off (Off-mode) were examined. Repeated measurements of heart rate variability (HRV) indices, PM≤2.5μm in aerodynamic diameter (PM2.5) and noise level were conducted for each participant in different modes during the commute. We used linear mixed-effects models to associate HRV indices with in-car PM2.5. We found that decreases in HRV indices were associated with increased levels of in-car PM2.5. For Off-mode, an interquartile range (IQR) increase in in-car PM2.5 with 15-min moving average was associated with 2.7% and 4.1% decreases in standard deviation of NN intervals (SDNN) and the square root of the mean of the sum of the squares of differences between adjacent NN intervals (r-MSSD), respectively. During OA and IA modes, participants showed slight decreases in SDNN (OA mode: 0.1%; IA mode: 1.3%) and r-MSSD (OA mode: 1.1%; IA mode: 1.8%) by an IQR increase in in-car PM2.5 with 15-min moving average. We concluded that in-car PM2.5 is associated with autonomic alteration. Utilization of the car's AC system can improve air quality and modify the effects of in-car PM2.5 on HRV indices among human subjects during the commute.

KW - Air conditioning system

KW - Car

KW - Epidemiology

KW - Heart rate variability

KW - Indoor air pollution

KW - Particulate matter

UR - http://www.scopus.com/inward/record.url?scp=84875608509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875608509&partnerID=8YFLogxK

U2 - 10.1016/j.scitotenv.2013.02.097

DO - 10.1016/j.scitotenv.2013.02.097

M3 - Article

C2 - 23523729

AN - SCOPUS:84875608509

VL - 452-453

SP - 309

EP - 313

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -