Improved predictive ability of the Montreal Cognitive Assessment for diagnosing dementia in a community-based study

Rong-Long Shiu, Yen Chun Fan, Ya Li Huang, Jui Wang, Wei-Hung Chen, Hou Chang Chiu, Chyi Huey Bai

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

Introduction: We compared the predictive ability of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a community-based study. Methods: A total of 276 people aged 60 years or older were enrolled. All of the participants were administered face-to-face interview questionnaires and MoCA and MMSE examinations. The receiver operating characteristic curve method and area under curve were performed to assess the predictive ability for diagnosing dementia. Results: The 276 participants had a mean age of 67.9 ± 6.1 years and mean education duration of 11.4 ± 4.0 years. In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78 %) and excellent specificity (94 %) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups. Conclusion: Our study determined a higher predictive ability in the MoCA than in the MMSE for diagnosing dementia according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria in a community-based sample with a broader range of education level.
原文英語
期刊Alzheimer's Research and Therapy
DOIs
出版狀態接受/付印 - 十一月 9 2015

指紋

Aptitude
Dementia
Diagnostic and Statistical Manual of Mental Disorders
Area Under Curve
Education
ROC Curve
Interviews

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Cognitive Neuroscience

引用此文

Improved predictive ability of the Montreal Cognitive Assessment for diagnosing dementia in a community-based study. / Shiu, Rong-Long; Fan, Yen Chun; Huang, Ya Li; Wang, Jui; Chen, Wei-Hung; Chiu, Hou Chang; Bai, Chyi Huey.

於: Alzheimer's Research and Therapy, 09.11.2015.

研究成果: 雜誌貢獻文章

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abstract = "Introduction: We compared the predictive ability of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a community-based study. Methods: A total of 276 people aged 60 years or older were enrolled. All of the participants were administered face-to-face interview questionnaires and MoCA and MMSE examinations. The receiver operating characteristic curve method and area under curve were performed to assess the predictive ability for diagnosing dementia. Results: The 276 participants had a mean age of 67.9 ± 6.1 years and mean education duration of 11.4 ± 4.0 years. In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78 {\%}) and excellent specificity (94 {\%}) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups. Conclusion: Our study determined a higher predictive ability in the MoCA than in the MMSE for diagnosing dementia according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria in a community-based sample with a broader range of education level.",
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AU - Chen, Wei-Hung

AU - Chiu, Hou Chang

AU - Bai, Chyi Huey

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N2 - Introduction: We compared the predictive ability of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a community-based study. Methods: A total of 276 people aged 60 years or older were enrolled. All of the participants were administered face-to-face interview questionnaires and MoCA and MMSE examinations. The receiver operating characteristic curve method and area under curve were performed to assess the predictive ability for diagnosing dementia. Results: The 276 participants had a mean age of 67.9 ± 6.1 years and mean education duration of 11.4 ± 4.0 years. In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78 %) and excellent specificity (94 %) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups. Conclusion: Our study determined a higher predictive ability in the MoCA than in the MMSE for diagnosing dementia according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria in a community-based sample with a broader range of education level.

AB - Introduction: We compared the predictive ability of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a community-based study. Methods: A total of 276 people aged 60 years or older were enrolled. All of the participants were administered face-to-face interview questionnaires and MoCA and MMSE examinations. The receiver operating characteristic curve method and area under curve were performed to assess the predictive ability for diagnosing dementia. Results: The 276 participants had a mean age of 67.9 ± 6.1 years and mean education duration of 11.4 ± 4.0 years. In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78 %) and excellent specificity (94 %) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups. Conclusion: Our study determined a higher predictive ability in the MoCA than in the MMSE for diagnosing dementia according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria in a community-based sample with a broader range of education level.

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