Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery

Shen Hu, Yun Yen, David Ann, David T. Wong

研究成果: 雜誌貢獻回顧型文獻同行評審

22 引文 斯高帕斯(Scopus)

摘要

Human saliva proteomics has proven to be a novel approach in the search for protein biomarkers for non-invasive detection of human cancers. This approach may also have implications within the process of anti-cancer drug discovery. Information from saliva proteomic measurements may contribute to the target discovery and validation, assessment of efficacy and toxicity of candidate drugs, identification of disease subgroups, and prediction of responses of individual patients. In this article, we aim to give a brief overview on human saliva proteome analysis, as well as its applications to cancer biomarker discovery. Potential applications of saliva proteomics in anticancer drug discovery and development will also be discussed.

原文英語
頁(從 - 到)911-916
頁數6
期刊Drug Discovery Today
12
發行號21-22
DOIs
出版狀態已發佈 - 11月 1 2007
對外發佈

ASJC Scopus subject areas

  • 藥理
  • 藥物發現

指紋

深入研究「Implications of salivary proteomics in drug discovery and development: a focus on cancer drug discovery」主題。共同形成了獨特的指紋。

引用此