Impact of the menstrual cycle on immunologic markers in HIV-infected Taiwanese women

Kuang Han Chao, Ming Yih Wu, Mei Jou Chen, Chien Ching Hung, Hong Nerng Ho

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Objective: This study tested the relationship between cellular immunity and the menstrual cycle in Taiwanese HIV-infected and normal women. Methods: From October 1997 to October 2001, 21 HIV-seropositive women and 30 controls were enrolled in this study. Blood was sampled for hormone profile (estradiol and progesterone) and immunophenotyping with flow cytometry during the follicular and luteal phases. Immunophenotyping included total blood cell count, lymphocyte count, CD4+ cells, CD8+ cells, and their activation markers, including CD25, CD69, HLA-DR, and CD38. Results: The proportion of CD8+ T cells increased during the follicular phase and activating antigens (HLA-DR and CD38) were elevated on CD8+ T cells of HIV-seropositive women. All these alterations seemed unrelated to the menstrual cycle. Conclusions: The CD8+ T cells were increased and activated in women with HIV infection but these alterations were not affected by the menstrual cycle. Therefore, sex hormones seem not to affect the course of HIV infection.
原文英語
頁(從 - 到)42-47
頁數6
期刊Taiwanese Journal of Obstetrics and Gynecology
45
發行號1
DOIs
出版狀態已發佈 - 一月 1 2006
對外發佈

ASJC Scopus subject areas

  • 婦產科

指紋

深入研究「Impact of the menstrual cycle on immunologic markers in HIV-infected Taiwanese women」主題。共同形成了獨特的指紋。

引用此