Impact of Body Mass Index on Postoperative Outcome of Advanced Gastric Cancer After Curative Surgery

Yen Shu Lin, Kuo Hung Huang, Yuan Tzu Lan, Wen Liang Fang, Jen Hao Chen, Su Shun Lo, Mao Chih Hsieh, Anna Fen Yau Li, Shih Hwa Chiou, Chew Wun Wu

研究成果: 雜誌貢獻文章同行評審

21 引文 斯高帕斯(Scopus)

摘要

Introduction: The impact of body mass index (BMI) on the outcome of advanced gastric cancer surgery is controversial. Between December 1987 and December 2006, a total of 947 advanced gastric cancer patients receiving curative resection with retrieved lymph node number >15 were studied and divided into three groups according to BMI (30 kg/m2). Results and Discussion: With regard to comorbidities present prior to surgery, higher BMI patients were more likely to have heart disease, type 2 diabetes, and hypertension than lower BMI patients. Compared with BMI 2, higher BMI patients had longer operative time and more surgery-related morbidity. Multivariate Cox proportional-hazard analysis showed that age, pathological T and N categories, and lymphovascular invasion were independent prognostic factors. The initial recurrence patterns, 5-year overall survival, and cancer-specific survival were similar among the three groups. Conclusion: Only in stage III gastric cancer with BMI less than 25 kg/m2 patients receiving total gastrectomy had a more advanced pathological N category and a worse prognosis compared to those receiving subtotal gastrectomy. Higher BMI was associated with longer operative time and more surgery-related morbidity than lower BMI. BMI alone is not an independent prognostic factor.
原文英語
頁(從 - 到)1382-1391
頁數10
期刊Journal of Gastrointestinal Surgery
17
發行號8
DOIs
出版狀態已發佈 - 八月 2013

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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