Immunopathology of hepatitis B virus infection

Hsiu Ting Tsai, Tzu Hsin Tsai, Tsong Ming Lu, Chi Chiang Yang

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18 引文 斯高帕斯(Scopus)

摘要

The interaction between immune responses and hepatitis B virus (HBV) is coordinated between innate and adaptive immunity. Anti-HBs antibodies protect the host by blocking the binding ability of HBV. Anti-HBc antibodies are detected with persistent HBV infection. The presence of anti-HBe antibodies is often associated with recovery from active diseases and is clinically used as a benchmark to assess response to treatment. Our studies have revealed that the anti-HBV immunoglobulins secreted are different in subclass patterns in different HBV infection status populations. These revelations may help to understand HBV escape and persistent infection and to develop strategies for prevention and therapeutic management of HBV infection.

原文英語
頁(從 - 到)427-446
頁數20
期刊International Reviews of Immunology
27
發行號6
DOIs
出版狀態已發佈 - 十一月 2008
對外發佈Yes

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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