Idiopathic hypereosinophilic syndrome with eosinophilic myositis, peripheral neuropathy and central nervous system involvement

Jiann D. Lee, Sien Tsong Chen, Chi J. Chen, Chiung M. Chen, Long S. Ro

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

摘要

Idiopathic hypereosinophilic syndrome (HES) is a rare disorder marked by a sustained overproduction of eosinophils and a predilection for damage to multiple organ systems. Its neurologic involvement ranges from the central to the peripheral nervous system, and can be associated with eosinophilic myositis. We report a 68-year-old woman who had eosinophilia, eosinophilic dermatitis and eosinophilic pneumonia. She also suffered from numbness and weakness of the lower limbs. Because of long-lasting (>6 mo) eosinophilia (>1.5 x 109/L) in the peripheral blood and the fact that no other underlying causes of eosinophilia and neurologic involvement could be identified, a diagnosis of idiopathic hypereosinophilic syndrome was made. The muscle biopsy showed infiltration of inflammatory cells, including a few eosinophils (Liu's stain). Magnetic resonance images, motor evoked potentials, somatosensory evoked potentials and nerve conduction velocities also showed abnormalities in the central and peripheral nervous systems. The pathogenesis and treatments of HES are discussed in this report.

原文英語
頁(從 - 到)933-936
頁數4
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
95
發行號12
出版狀態已發佈 - 十二月 1996
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

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