Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report

I. Han Chiang, Yi Shu Liao, Niann Tzyy Dai, Hao Yu Chiao, Chang Yi Chou, Shyi Gen Chen, Tim Mo Chen, Shun Cheng Chang

研究成果: 雜誌貢獻回顧型文獻同行評審

7 引文 斯高帕斯(Scopus)


Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion. Management usually consists of systemic drug therapy, such as corticosteroids, sulfones, or immunosuppressants, either alone or in combination. Long-term use of these medications often has untold side effects. Hyperbaric oxygen therapy (HBOT) has been shown effective in the treatment of PG, reducing pain and tempering the need for medication. A case is presented of a 54-year-old woman with diabetes, hypertension, and a peptic ulcer who presented with painful, purulent ulcers on her buttocks, hands, and lower extremities of 2 weeks' duration. She was ultimately diagnosed with PG and provided 20 mg/day of oral prednisone for 1 week, tapered to 10 mg/day in the next week and then stopped. In addition, she received 12 sessions of HBOT-she breathed in 100% oxygen under 2.5 atmospheres absolute pressure for 90 minutes over 2 weeks. Her wounds healed without scarring. This excellent outcome including good wound healing, decreased pain, and reduced doses of systemic corticosteroids warrants additional study of the adjunctive use of HBOT for PG.
頁(從 - 到)32-36
期刊Ostomy Wound Management
出版狀態已發佈 - 5月 1 2016

ASJC Scopus subject areas

  • 內科學
  • 護理(全部)
  • 消化內科


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