Human papillomaviral load changes in low-grade squamous intraepithelial lesions of the uterine cervix

C. M. Ho, W. F. Cheng, T. Y. Chu, C. A. Chen, M. H. Chuang, S. F. Chang, C. Y. Hsieh

研究成果: 雜誌貢獻文章

27 引文 斯高帕斯(Scopus)

摘要

To better predict risk of progression of low-grade squamous intraepithelial lesions (LSILs) of the uterine cervix in women with human papillomavirus (HPV) infections, 294 baseline cervical specimens from women with LSILs were evaluated. Specimens were tested for HPV DNA using hybrid capture 2 (HC2) and PCR-reverse line blotting. 65 LSILs with HPV DNA types 16, 18, 52, or 58 were examined for physical status, E2/E6 ratio and viral load at two time points, along with patient age. Women with LSILs whose viral loads increased between baseline and 6 month follow-up had a 45% risk of developing HSIL (OR = 7.6, 95% CI = 1.9-29.4, P

原文英語
頁(從 - 到)1384-1389
頁數6
期刊British Journal of Cancer
95
發行號10
DOIs
出版狀態已發佈 - 十一月 20 2006

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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