Human genetics and assisted reproduction in endometriosis

Chien Wen Chen, Endah Rahmawati, Guan Lin Lai, Ya Ching Chou, Yun Yi Ma, Yi Xuan Lee, Chii Ruey Tzeng

研究成果: 書貢獻/報告類型章節

摘要

Endometriosis is a prevalent disease imposing detrimental impacts on female health and fecundity. Although detection of asymptomatic endometriosis is challenging at present, studies have revealed promising results for detecting asymptomatic endometriosis with a panel of biomarkers. Endometriosis is associated with blood trace metals. While blood zinc displays a protective role against endometriosis, the relationship between blood lead and endometriosis remains unclear. Phthalates disturb human endocrines and are associated with endometriosis and poor development of oocytes and embryos. For women with endometriosis suffering from infertility, assisted reproduction is the most efficient treatment. While the most appropriate treatment remains controversial in recurrent endometriosis, the cystectomy of the endometrioma should always be replaced by cyst aspiration in order to preserve the ovarian reserve. Although the association between adenomyosis and infertility has not been well established, assisted reproduction following pituitary down-regulation or surgical removal of the endometriotic lesions are both efficient management techniques for infertile women with adenomyosis.

原文英語
主出版物標題Human Reproductive and Prenatal Genetics
發行者Elsevier
頁面495-514
頁數20
ISBN(電子)9780128135709
ISBN(列印)9780128135716
DOIs
出版狀態已發佈 - 一月 1 2018

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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