HUMAN β‐ENDORPHIN: SYNTHESIS AND BIOLOGICAL ACTIVITY OF ANALOGS WITH SUBSTITUTIONS IN POSITIONS 2, 9, 18, 27 AND 31

HIN‐WING ‐W YEUNG, DONALD YAMASHIRO, LIANG‐FU ‐F TSENG, WEN‐CHANG ‐C CHANG, CHOH HAO LI

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

摘要

Four analogs of the opioid peptide human β‐endorphin (βh‐EP) have been synthesized: [d‐Lys9,Phe27,Gly31]‐βh‐EP, [d‐Phe18,Phe27,Gly31)‐βh‐EP, [d‐Thr2,d‐Lys9,Phe27,Gly31]‐βh‐EP, and [d‐Thr2,d‐Phe18,Phe27,Gly31]‐βh‐EP. All are practically indistinguishable from βh‐EP in the guinea pig ileum assay. All show diminished analgesic potency in the mouse tail‐flick assay.
原文英語
頁(從 - 到)235-238
頁數4
期刊International Journal of Peptide and Protein Research
17
發行號2
DOIs
出版狀態已發佈 - 一月 1 1981
對外發佈Yes

ASJC Scopus subject areas

  • Biochemistry

指紋 深入研究「HUMAN β‐ENDORPHIN: SYNTHESIS AND BIOLOGICAL ACTIVITY OF ANALOGS WITH SUBSTITUTIONS IN POSITIONS 2, 9, 18, 27 AND 31」主題。共同形成了獨特的指紋。

  • 引用此