HUMAN β‐ENDORPHIN Immunoreactivity of Synthetic Analogs with Various Chain Lengths

WEN‐CHANG ‐C CHANG, HIN‐WING ‐W YEUNG, CHOH HAO LI

研究成果: 雜誌貢獻文章

14 引文 (Scopus)

摘要

Immunoreactivity of synthetic human β‐endorphin analogs with various chain lengths has been examined using a specific radioimmunoassay. It was found that β‐endorphin‐(1–21) and analogs of shortened chain exhibit no immunoreactivity, whereas β‐endorphin‐(1–15) possesses significant in vitro opiate activity. It appears that immunoreactivity of β‐endorphin resides in the COOH‐terminal segment of residues (22–31). The data also show the lack of correlation between opiate and immunological activities of β‐endorphin.
原文英語
頁(從 - 到)278-281
頁數4
期刊International Journal of Peptide and Protein Research
13
發行號3
DOIs
出版狀態已發佈 - 一月 1 1979
對外發佈Yes

指紋

Endorphins
Chain length
Opiate Alkaloids
Radioimmunoassay

ASJC Scopus subject areas

  • Biochemistry

引用此文

HUMAN β‐ENDORPHIN Immunoreactivity of Synthetic Analogs with Various Chain Lengths. / CHANG, WEN‐CHANG ‐C; YEUNG, HIN‐WING ‐W; LI, CHOH HAO.

於: International Journal of Peptide and Protein Research, 卷 13, 編號 3, 01.01.1979, p. 278-281.

研究成果: 雜誌貢獻文章

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abstract = "Immunoreactivity of synthetic human β‐endorphin analogs with various chain lengths has been examined using a specific radioimmunoassay. It was found that β‐endorphin‐(1–21) and analogs of shortened chain exhibit no immunoreactivity, whereas β‐endorphin‐(1–15) possesses significant in vitro opiate activity. It appears that immunoreactivity of β‐endorphin resides in the COOH‐terminal segment of residues (22–31). The data also show the lack of correlation between opiate and immunological activities of β‐endorphin.",
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