Histological evaluation of socket preservation with different bone grafting materials

研究成果: 雜誌貢獻文章

2 引文 (Scopus)

摘要

The aim of this study was to compare different bone grafting materials and their contribution to socket preservation. In six beagle dogs, bilateral mandibular second, third, and fourth premolars were hemisectioned and extracted. The following four treatment modalities were randomly allocated: (1) empty control site, (2) collagen plug, (3) Bio Oss-collagen, (4) HA/β-TCP- collagen. After 2 and 4 weeks, the animals were sacrificed, and decalcified sections were obtained for histological analysis. New bone formation was homogeneous, progressive, and centripetal in all materials. Remodeling as well as the calcification of the newly formed bone was observed. In addition, well-connected trabeculae surrounding the degraded materials were observed. Nearly mature bone, which demonstrated less cellular, more mineralized, and structurally more organized into lamellar bone was noted in HA/β-TCP- collagen composite. In this study, Bio Oss-collagen and HA/β-TCP-collagen produced a newly biomimetic composite biomaterial and could prove to be a superior bone substitute material, both structurally and functionally, which could be used in the repair of bone defects collagen composite.
原文英語
頁(從 - 到)225-230
頁數6
期刊Journal of Polymer Engineering
34
發行號3
DOIs
出版狀態已發佈 - 五月 1 2014

指紋

Collagen
Bone
Composite materials
Bone Substitutes
Biomimetics
Biocompatible Materials
Biomaterials
Animals
Repair
Defects

ASJC Scopus subject areas

  • Materials Chemistry
  • Polymers and Plastics
  • Chemical Engineering(all)

引用此文

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abstract = "The aim of this study was to compare different bone grafting materials and their contribution to socket preservation. In six beagle dogs, bilateral mandibular second, third, and fourth premolars were hemisectioned and extracted. The following four treatment modalities were randomly allocated: (1) empty control site, (2) collagen plug, (3) Bio Oss-collagen, (4) HA/β-TCP- collagen. After 2 and 4 weeks, the animals were sacrificed, and decalcified sections were obtained for histological analysis. New bone formation was homogeneous, progressive, and centripetal in all materials. Remodeling as well as the calcification of the newly formed bone was observed. In addition, well-connected trabeculae surrounding the degraded materials were observed. Nearly mature bone, which demonstrated less cellular, more mineralized, and structurally more organized into lamellar bone was noted in HA/β-TCP- collagen composite. In this study, Bio Oss-collagen and HA/β-TCP-collagen produced a newly biomimetic composite biomaterial and could prove to be a superior bone substitute material, both structurally and functionally, which could be used in the repair of bone defects collagen composite.",
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AU - Chang, Wei Jen

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