High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field

Yu Nan Lin, Peng Chun Chen, Ren Guei Wu, Li Chern Pan, Fan Gang Tseng

研究成果: 書貢獻/報告類型會議貢獻

摘要

In this study, we propose a microfluidic device for differentiating sperm motilities by interacting sperm's flowing upstream property with dual gradient flow field. Non-motile sperms will be flushed out of the second acceleration flow field while the motile sperms will be separated by the first gradient flow field with decreasing flow speed according to their motilities. This gentle sperm sorting process can accumulate millions of motile sperms from billions of sperms in half an hour, and categorized them into 3 different levels, suitable for in vitro fertilization (IVF) and artificial insemination (AI) applications.

原文英語
主出版物標題17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者Chemical and Biological Microsystems Society
頁面645-647
頁數3
1
ISBN(列印)9781632666246
出版狀態已發佈 - 2013
事件17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, 德国
持續時間: 十月 27 2013十月 31 2013

其他

其他17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家德国
城市Freiburg
期間10/27/1310/31/13

ASJC Scopus subject areas

  • Bioengineering

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  • 引用此

    Lin, Y. N., Chen, P. C., Wu, R. G., Pan, L. C., & Tseng, F. G. (2013). High-throughput sperm sorting by sperm flowing upstream in a dual gradient flow field. 於 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (卷 1, 頁 645-647). Chemical and Biological Microsystems Society.