High seroprevalence of Toxocara antibodies in pregnant women attending an antenatal clinic at a university hospital in Ile-Ife, Nigeria

Kemisola Ikotun, Oluyomi Sowemimo, Chia Mei Chou, Kayode Ajenifuja, Ting Wu Chuang, Samuel Asaolu, Olaoluwa Akinwale, Vincent Gyang, Timothy Nwafor, Emmanuel Henry, Chia Kwung Fan

研究成果: 雜誌貢獻文章同行評審

1 引文 斯高帕斯(Scopus)

摘要

Background: Human toxocariasis is a neglected zoonotic disease and its impact on human health is underestimated. Studies investigating the occurrence of toxocariasis in pregnancy are very scarce in Nigeria. This study investigated the seroprevalence of Toxocara spp. antibodies as well as the possible risk factors in pregnant women who routinely attended an antenatal clinic in a university hospital in Ile-Ife, Osun state. Methods: Blood samples were collected from 413 participating pregnant women between October 2017 and February 2018. Epidemiological data were obtained through a structured questionnaire. The sera were screened for anti-Toxocara IgG antibodies by western blot technique based on Toxocara canis larval excretory-secretory antigens, targeting low molecular weight bands of 24-35 kDa, specifically for T. canis infection. Results: The overall seroprevalence was 92.49% (382/413). There was no significant difference in the seroprevalence rate of Toxocara spp. infection between pregnant women aged ≤30 y and those aged >30 y (91.63 vs 93.33%; OR 1.28, 95% CI 0.61 to 2.67, p=0.511). The seroprevalence rate increased with the number of miscarriages but there was no statistical significance (p>0.05). Moreover, no significant associations were found between Toxocara spp. seropositivity and other studied risk factors (p>0.05). Conclusion: The high seroprevalence of Toxocara spp. in pregnant Nigerian women needs comprehensive health education regarding personal hygiene and how to avoid exposure to this parasite infection.
原文英語
頁(從 - 到)301-307
頁數7
期刊Transactions of the Royal Society of Tropical Medicine and Hygiene
114
發行號4
DOIs
出版狀態已發佈 - 四月 8 2020

ASJC Scopus subject areas

  • 寄生物學
  • 公共衛生、環境和職業健康
  • 傳染性疾病

指紋

深入研究「High seroprevalence of Toxocara antibodies in pregnant women attending an antenatal clinic at a university hospital in Ile-Ife, Nigeria」主題。共同形成了獨特的指紋。

引用此