Herniated blastomere following chemically assisted hatching may result in monozygotic twins

Tzong Chyi Sheen, Su-Ru Chen, Heng Kien Au, Yi Yi Chien, Ko Yi Wu, Chii Ruey Tzeng

研究成果: 雜誌貢獻文章

12 引文 (Scopus)

摘要

Objective: To explore a possible mechanism of the increasing incidence of monozygotic twins following assisted hatching of human embryos. Design: Case report. Setting: Clinical research center in a medical school teaching hospital. Patient(s): A 37-year-old infertile woman with repeated IVF failures. Intervention(s): Assisted hatching of the day 3 embryos using acidic Tyrode's solution. Main Outcome Measure(s): The morphology of the zona-drilled embryos and the pregnancy outcome. Result(s): After assisted hatching, a herniated blastomere through an oversized opening in the zona pellucida was found in one embryo. The transfer of two zona-drilled embryos resulted in a triplet pregnancy. Conclusion(s): Large openings in the zona pellucida following chemically assisted hatching may cause premature hatching of the blastomeres and may be implicated in the occurrence of monozygotic twins.

原文英語
頁(從 - 到)442-444
頁數3
期刊Fertility and Sterility
75
發行號2
DOIs
出版狀態已發佈 - 2001

指紋

Blastomeres
Monozygotic Twins
Embryonic Structures
Zona Pellucida
Herpes Zoster
Triplet Pregnancy
Pregnancy Outcome
Medical Schools
Teaching Hospitals
Outcome Assessment (Health Care)
Incidence
Research

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

引用此文

Herniated blastomere following chemically assisted hatching may result in monozygotic twins. / Sheen, Tzong Chyi; Chen, Su-Ru; Au, Heng Kien; Chien, Yi Yi; Wu, Ko Yi; Tzeng, Chii Ruey.

於: Fertility and Sterility, 卷 75, 編號 2, 2001, p. 442-444.

研究成果: 雜誌貢獻文章

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title = "Herniated blastomere following chemically assisted hatching may result in monozygotic twins",
abstract = "Objective: To explore a possible mechanism of the increasing incidence of monozygotic twins following assisted hatching of human embryos. Design: Case report. Setting: Clinical research center in a medical school teaching hospital. Patient(s): A 37-year-old infertile woman with repeated IVF failures. Intervention(s): Assisted hatching of the day 3 embryos using acidic Tyrode's solution. Main Outcome Measure(s): The morphology of the zona-drilled embryos and the pregnancy outcome. Result(s): After assisted hatching, a herniated blastomere through an oversized opening in the zona pellucida was found in one embryo. The transfer of two zona-drilled embryos resulted in a triplet pregnancy. Conclusion(s): Large openings in the zona pellucida following chemically assisted hatching may cause premature hatching of the blastomeres and may be implicated in the occurrence of monozygotic twins.",
keywords = "Assisted hatching, Blastomere herniation, Monozygotic twins",
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T1 - Herniated blastomere following chemically assisted hatching may result in monozygotic twins

AU - Sheen, Tzong Chyi

AU - Chen, Su-Ru

AU - Au, Heng Kien

AU - Chien, Yi Yi

AU - Wu, Ko Yi

AU - Tzeng, Chii Ruey

PY - 2001

Y1 - 2001

N2 - Objective: To explore a possible mechanism of the increasing incidence of monozygotic twins following assisted hatching of human embryos. Design: Case report. Setting: Clinical research center in a medical school teaching hospital. Patient(s): A 37-year-old infertile woman with repeated IVF failures. Intervention(s): Assisted hatching of the day 3 embryos using acidic Tyrode's solution. Main Outcome Measure(s): The morphology of the zona-drilled embryos and the pregnancy outcome. Result(s): After assisted hatching, a herniated blastomere through an oversized opening in the zona pellucida was found in one embryo. The transfer of two zona-drilled embryos resulted in a triplet pregnancy. Conclusion(s): Large openings in the zona pellucida following chemically assisted hatching may cause premature hatching of the blastomeres and may be implicated in the occurrence of monozygotic twins.

AB - Objective: To explore a possible mechanism of the increasing incidence of monozygotic twins following assisted hatching of human embryos. Design: Case report. Setting: Clinical research center in a medical school teaching hospital. Patient(s): A 37-year-old infertile woman with repeated IVF failures. Intervention(s): Assisted hatching of the day 3 embryos using acidic Tyrode's solution. Main Outcome Measure(s): The morphology of the zona-drilled embryos and the pregnancy outcome. Result(s): After assisted hatching, a herniated blastomere through an oversized opening in the zona pellucida was found in one embryo. The transfer of two zona-drilled embryos resulted in a triplet pregnancy. Conclusion(s): Large openings in the zona pellucida following chemically assisted hatching may cause premature hatching of the blastomeres and may be implicated in the occurrence of monozygotic twins.

KW - Assisted hatching

KW - Blastomere herniation

KW - Monozygotic twins

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