Herniated blastomere following chemically assisted hatching may result in monozygotic twins

Tzong Chyi Sheen, Su-Ru Chen, Heng Kien Au, Yi Yi Chien, Ko Yi Wu, Chii Ruey Tzeng

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

Objective: To explore a possible mechanism of the increasing incidence of monozygotic twins following assisted hatching of human embryos. Design: Case report. Setting: Clinical research center in a medical school teaching hospital. Patient(s): A 37-year-old infertile woman with repeated IVF failures. Intervention(s): Assisted hatching of the day 3 embryos using acidic Tyrode's solution. Main Outcome Measure(s): The morphology of the zona-drilled embryos and the pregnancy outcome. Result(s): After assisted hatching, a herniated blastomere through an oversized opening in the zona pellucida was found in one embryo. The transfer of two zona-drilled embryos resulted in a triplet pregnancy. Conclusion(s): Large openings in the zona pellucida following chemically assisted hatching may cause premature hatching of the blastomeres and may be implicated in the occurrence of monozygotic twins.

原文英語
頁(從 - 到)442-444
頁數3
期刊Fertility and Sterility
75
發行號2
DOIs
出版狀態已發佈 - 2001

ASJC Scopus subject areas

  • 婦產科

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