Hepatotoxicity and hepatocarcinogenicity in rats fed squid with or without exogenous nitrite

Agriculture & Biology

• hepatotoxicity 84%
• squid 78%
• nitrites 70%
• trimethylamine 44%
• hepatoma 38%
• rats 36%
• dimethylamine 33%
• amines 22%
• oxides 21%
• seafoods 13%
• liver 13%
• alanine transaminase 12%
• aspartate transaminase 11%
• hemorrhage 11%
• transferases 11%
• glutamates 10%
• neutrophils 10%
• necrosis 10%
• ascorbic acid 9%
• incidence 8%
• diet 5%

Medicine & Life Sciences

• Decapodiformes 98%
• Nitrites 76%
• dimethylamine 38%
• trimethyloxamine 35%
• Hepatocellular Carcinoma 28%
• Amines 24%
• Seafood 15%
• Neutrophil Infiltration 13%
• Liver 12%
• Transferases 11%
• Aspartate Aminotransferases 11%
• Ascorbic Acid 11%
• Alanine Transaminase 11%
• Glutamic Acid 10%
• Necrosis 8%
• Diet 7%
• Hemorrhage 7%
• Incidence 5%
• Serum 5%

Chemical Compounds

• Trimethylamine N-Oxide 100%
• Dimethylamine 83%
• Amine 44%
• Trimethylamine 42%
• Vitamin C 41%