Heart Rate Variability During Hemodialysis and Following Renal Transplantation

Y. W. Yang, C. H. Wu, M. K. Tsai, T. B.J. Kuo, C. C.H. Yang, P. H. Lee

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19 引文 斯高帕斯(Scopus)


Previous studies have shown awareness of uremic dysfunction in end-stage renal disease (ESRD) patients. Dysautonomia in ESRD patients may be reversible after renal transplantation. We used a power spectral analysis (PSA) of heart rate variability (HRV) to assess alterations of autonomic activity in 14 controls and 14 nondiabetic hemodialysis ESRD patients who had undergone renal transplantation. Compared with matched control subjects, the power frequency determinations of low frequency (LF; 3.42 ln(ms2) vs 6.38 ln(ms2); P < .05 high frequency (HF; 2.29 ln(ms2) vs 5.27 ln(ms2); P < .05)), and total power (TP; 5.39 ln(ms2) vs 7.53 ln(ms2); P < .05) were significantly suppressed in ESRD patients undergoing hemodialysis. ESRD patients showed significantly improved HRV after renal transplantation. After renal transplantation, there was no significant difference in the TP (6.82 ln(ms2) vs 7.53 ln(ms2); P = .15) component between measurements in both patient subgroups. We further divided the ESRD patients into 2 groups based on their pretransplantation HRV, observing alterations in HRV after renal transplantation. Patients with significantly improved HRV were those with more suppressed HRV before transplantation (HF <3 In(ms2). Autonomic dysfunction in ESRD patients was not irreversible even if severe, and recovery was observed as early as 6 months after transplantation.
頁(從 - 到)1637-1640
期刊Transplantation Proceedings
出版狀態已發佈 - 六月 2010

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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