Heart failure enhances arrhythmogenesis in pulmonary veins

Shih Lin Chang, Yao Chang Chen, Yung Hsin Yeh, Yu Jun Lai, Hung I. Yeh, Cheng I. Lin, Yung Kuo Lin, Yenn Jiang Lin, Tsu Juey Wu, Yi Kung Huang, Shih Ann Chen, Yi Jen Chen

研究成果: 雜誌貢獻文章同行評審

15 引文 斯高帕斯(Scopus)

摘要

1.Heart failure (HF) predisposes to atrial fibrillation (AF) as a result of substrate remodelling. The present study aimed to investigate the impact of HF on the electrical remodelling of the pulmonary veins (PV) and left atrium (LA). 2.The electrical activity was recorded in LA and PV from control rabbits and rabbits with rapid ventricular pacing-induced HF, using a multi-electrode array system and conventional microelectrodes. 3.Compared with the control-PV (n=21), the HF-PV (n=13) had a higher incidence and frequency of rapid pacing-induced spontaneous activity (85 vs 29%, P=0.005; 3.5±0.2 vs 1.7±0.1Hz, P

原文英語
頁(從 - 到)666-674
頁數9
期刊Clinical and Experimental Pharmacology and Physiology
38
發行號10
DOIs
出版狀態已發佈 - 十月 2011

ASJC Scopus subject areas

  • 生理學
  • 生理學(醫學)
  • 藥理

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