Graft-versus-host reaction, ranging from mild to severe, was observed in three of seven patients who had had an allogeneic bone-marrow engraftment from their HL-A antigen identical siblings. Two patients died as a direct result of this complication of marrow transplantation.
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Graw, R. G., Herzig, G. P., Rogentine, G. N., Yankee, R. A., Leventhal, B. G., Whang-Peng, J., Halterman, R. H., Krüger, G., Berard, C., & Henderson, E. S. (1970). GRAFT-VERSUS-HOST REACTION COMPLICATING HL-A MATCHED BONE-MARROW TRANSPLANTATION. The Lancet, 296(7682), 1053-1055. https://doi.org/10.1016/S0140-6736(70)90285-0