Geriatric Nutritional Risk Index, a Simplified Nutritional Screening Index, Is a Strong Predictor of Handgrip Strength in Renal Transplant Recipients

I. H. Lin, T. C. Wong, S. W. Nien, H. H. Wang, Y. J. Chiang, S. H. Yang

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

Background: The Geriatric Nutritional Risk Index (GNRI) is a useful predictor of prognosis in older patients and those receiving hemodialysis. However, the predictive value of the GNRI in renal transplant recipients (RTRs) is unclear. In this study we investigated the correlation between the GNRI and muscle function, as indicated by handgrip strength (HGS). Methods: A cross-sectional study was performed on 42 RTRs (50% women), with a mean age of 49.0 ± 10.8 years. The GNRI was derived from patients’ body weight and serum albumin level by using the following equation: GNRI = [14.89 × albumin (g/dL)] + [41.7 × (body weight/ideal body weight)]. HGS was evaluated in dominant arms; HGS measurement was repeated 3 times, and the highest value was used. Multivariable stepwise regression analyses were performed to obtain adjusted correlates, and the significance levels for entry and remaining were set at 0.1. Results: The mean values of the GNRI and HGS were 105.0 ± 5.4 and 29.0 ± 9.4, respectively. The GNRI was positively correlated with HGS (r = 0.36, P =.02). Linear and stepwise multivariable adjustment analyses revealed that the homeostatic model assessment of insulin resistance (HOMA-IR) and GNRI were independent determinants of HGS (β HOMA-IR = 0.53 and β GNRI = 0.43, adjusted R 2 = 0.45) after adjustment for age, sex, total muscle mass, and C-reactive protein level as covariates. Conclusion: This study has shown that the GNRI is a favorable predictor of muscle function in RTRs.
原文英語
頁(從 - 到)2509-2514
頁數6
期刊Transplantation Proceedings
50
發行號8
DOIs
出版狀態已發佈 - 十月 1 2018

ASJC Scopus subject areas

  • Surgery
  • Transplantation

指紋 深入研究「Geriatric Nutritional Risk Index, a Simplified Nutritional Screening Index, Is a Strong Predictor of Handgrip Strength in Renal Transplant Recipients」主題。共同形成了獨特的指紋。

引用此