Gender differences in the relationship between depression and cardiac autonomic function among community elderly

Hsi Chung Chen, Cheryl C H Yang, Terry B J Kuo, Tung Ping Su, Pesus Chou

研究成果: 雜誌貢獻文章同行評審

27 引文 斯高帕斯(Scopus)

摘要

Objective: The mechanism underlying the differential effect of depression on morbidity and mortality in men and women remains unknown. This survey was designed to examine gender effects on the relationship between depressive symptoms and cardiac autonomic function among community dwelling elderly. Methods: Six hundred and six randomly selected community-dwelling elderly men and women ≥65 years of age were enrolled. Depressive symptoms were assessed with the Hospital Anxiety and Depression Scale. Cardiac autonomic function was evaluated by measuring heart rate variability (HRV) parameters. Frequency-domain indices of HRV were obtained. Results:Among the subjects, 58.4% were male with a mean age of 77.9 years. Stratified analyses by gender revealed a dose-response association between depressive symptoms and lower cardiac vagal control among elderly males ( p=0.003). Male subjects with mild depressive symptoms (depression scores: 5-6) showed prominent cardiac sympathetic predominance compared with the reference group (depression scores:<5) ( p=0.005). In contrast, these findings did not exist among elderly females. Conclusions: The association of depressive symptoms with poor cardiac vagal control and sympathetic predominance was more robust among elderly males than females. This finding may help explain gender differences in the association of depression with morbidity and mortality.
原文英語
頁(從 - 到)314-322
頁數9
期刊International Journal of Geriatric Psychiatry
25
發行號3
DOIs
出版狀態已發佈 - 三月 2010
對外發佈

ASJC Scopus subject areas

  • 老年病學和老年學
  • 精神病學和心理健康

指紋

深入研究「Gender differences in the relationship between depression and cardiac autonomic function among community elderly」主題。共同形成了獨特的指紋。

引用此