Gender difference in intraocular pressure and incidence of metabolic syndrome: A community-based cohort study in matsu, Taiwan

Raymond N. Kuo, Chia Ching Yang, Amy Ming Fang Yen, Tzeng Ying Liu, Ming Wei Lin, Sam Li Sheng Chen

研究成果: 雜誌貢獻文章

摘要

Background: We aimed to assess the effect of intraocular pressure (IOP) on incident metabolic syndrome (MetS) using a longitudinal follow-up of screening cohort in contrast to most of previous studies addressing the association between both. Methods: The empirical data were derived from a community-based integrated screening program in Matsu during the period 2003 to 2010. A total of 1347 participants older than 30 years were enrolled in this study. With the enrollment of 1056 participants with MetS free at baseline, the cohort with IOP measurement in 2003 were followed up over time to identify incident MetS to elucidate the temporal sequence of both. Results: The statistically significant effect noted was that elevated IOP (≥15 mmHg vs. <15 mmHg) had 1.46-fold risk for developing incident MetS (adjusted relative ratio [aRR]: 1.46; 95% confidence interval [CI]: 1.08-1.99) for both sex combined, particularly in men (aRR: 1.66; 95% CI: 1.13-2.45) but not in women. The finding that elevated IOP occurred before the presence of high blood pressure was noted in both men and women, whereas men with elevated IOP may be concomitant with more individual components (severity) of MetS earlier than women with elevated IOP. Conclusions: Elevated IOP leading to the risk for incident or severe MetS was noted in men but not in women. Evidence on this temporal sequence revealed the possibility of showing signs of elevated IOP before the development of MetS, which indicates the necessity of monitoring IOP in routine health check-up for prevention of MetS-related chronic diseases.
原文英語
頁(從 - 到)334-340
頁數7
期刊Metabolic Syndrome and Related Disorders
17
發行號6
DOIs
出版狀態已發佈 - 七月 1 2019

指紋

Intraocular Pressure
Taiwan
Cohort Studies
Incidence
Confidence Intervals
Chronic Disease
Hypertension
Health

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

引用此文

Gender difference in intraocular pressure and incidence of metabolic syndrome : A community-based cohort study in matsu, Taiwan. / Kuo, Raymond N.; Yang, Chia Ching; Yen, Amy Ming Fang; Liu, Tzeng Ying; Lin, Ming Wei; Chen, Sam Li Sheng.

於: Metabolic Syndrome and Related Disorders, 卷 17, 編號 6, 01.07.2019, p. 334-340.

研究成果: 雜誌貢獻文章

Kuo, Raymond N. ; Yang, Chia Ching ; Yen, Amy Ming Fang ; Liu, Tzeng Ying ; Lin, Ming Wei ; Chen, Sam Li Sheng. / Gender difference in intraocular pressure and incidence of metabolic syndrome : A community-based cohort study in matsu, Taiwan. 於: Metabolic Syndrome and Related Disorders. 2019 ; 卷 17, 編號 6. 頁 334-340.
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abstract = "Background: We aimed to assess the effect of intraocular pressure (IOP) on incident metabolic syndrome (MetS) using a longitudinal follow-up of screening cohort in contrast to most of previous studies addressing the association between both. Methods: The empirical data were derived from a community-based integrated screening program in Matsu during the period 2003 to 2010. A total of 1347 participants older than 30 years were enrolled in this study. With the enrollment of 1056 participants with MetS free at baseline, the cohort with IOP measurement in 2003 were followed up over time to identify incident MetS to elucidate the temporal sequence of both. Results: The statistically significant effect noted was that elevated IOP (≥15 mmHg vs. <15 mmHg) had 1.46-fold risk for developing incident MetS (adjusted relative ratio [aRR]: 1.46; 95{\%} confidence interval [CI]: 1.08-1.99) for both sex combined, particularly in men (aRR: 1.66; 95{\%} CI: 1.13-2.45) but not in women. The finding that elevated IOP occurred before the presence of high blood pressure was noted in both men and women, whereas men with elevated IOP may be concomitant with more individual components (severity) of MetS earlier than women with elevated IOP. Conclusions: Elevated IOP leading to the risk for incident or severe MetS was noted in men but not in women. Evidence on this temporal sequence revealed the possibility of showing signs of elevated IOP before the development of MetS, which indicates the necessity of monitoring IOP in routine health check-up for prevention of MetS-related chronic diseases.",
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