Gastric substitution for resectable carcinoma of the esophagus: An analysis of 368 cases

Liang Shun Wang, Min Hsiung Huang, Biing Shiun Huang, Kwang Yu Chien

研究成果: 雜誌貢獻文章同行評審

110 引文 斯高帕斯(Scopus)

摘要

Between 1974 and 1984, 1,188 patients with esophageal malignancies were treated in the Division of Thoracic Surgery of Veterans General Hospital, Taipei. The rate of resectability was 42.6%. Since 1974, the stomach has been used as esophageal substitute, and through 1984, a total of 368 patients were collected. The routes of reconstruction included retrosternal (77.2%), posteromediastinal (7.1%), and intrathoracic (15.7%). The rates of postoperative complications and surgical mortality in these 368 patients were 26.3% and 6.5%, respectively. Leakage of anastomosis was the most frequent complication. The incidence of stricture of esophagogastrostomy was 25.5%. All strictures were relieved by esophageal dilations. An average of 3.9 esophageal dilations were performed per patient (range, 1 to 15). Radical lymph node dissection was not routinely performed in our series. The actuarial 2-year and 5-year survival rates were 26.4% and 7.6%, respectively. Among 76 patients undergoing cervical esophagogastrostomy and surviving for more than 1 year, late complications occurred as follows: acid/bile regurgitation, 46.1%; postprandial fullness of abdomen, 38.2%; dumping syndrome, 13.2%; distended stomach with dyspnea, 11.8%; aspiration pneumonia, 6.6%; and gastric ulcer, 6.6%. Moreover, compared with patients without pyloroplasty, those with pyloroplasty were found to have a higher incidence of bile regurgitation (55.5% versus 8.6%), dumping syndrome (33.3% versus 6.9%), aspiration pneumonia (16.7% versus 3.4%), and gastric ulcer (22.2% versus 1.7%). In studies of total esophageal substitute transit time and technetium 99m-HIDA test (n = 33), we found that pyloroplasty or pyloromyotomy failed to normalize the disturbed gastric emptying but resulted in a high incidence of enterogastric bile reflux. Thus, we conclude that routine pyloroplasty or pyloromyotomy is not necessary. Although more than half of our patients had experience with late complications of gastric transplantation, most of them (>80%) can take care of themselves and their daily work after proper medication and physical therapy, if there is no tumor recurrence or other associated diseases.

原文英語
頁(從 - 到)289-294
頁數6
期刊Annals of Thoracic Surgery
53
發行號2
DOIs
出版狀態已發佈 - 1992
對外發佈Yes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

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