From white to beige adipocytes: Therapeutic potential of dietary molecules against obesity and their molecular mechanisms

Siyu Wang, Min Hsiung Pan, Wei Lun Hung, Yen Chen Tung, Chi Tang Ho

研究成果: 雜誌貢獻回顧型文獻

7 引文 斯高帕斯(Scopus)

摘要

The global incidence of obesity and its complications continue to rise along with a demand for novel therapeutic approaches. In addition to classic brown adipose tissue (BAT), the formation of brown-like adipocytes called beige adipocytes, within white adipose tissue (WAT), has attracted much attention as a therapeutic target due to its inducible features when stimulated, resulting in the dissipation of extra energy as heat. There are various dietary agents that are able to modulate the beige-development process by interacting with critical molecular signaling cascades, leading to the enhancement of thermogenesis. Although challenges still remain regarding the origin of the beige adipocytes, the crosstalk with activation of BAT and induction of the beiging of white fat may provide attractive potential strategies for management of obesity.
原文英語
頁(從 - 到)1263-1279
頁數17
期刊Food and Function
10
發行號3
DOIs
出版狀態已發佈 - 三月 1 2019

ASJC Scopus subject areas

  • Food Science

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