Formulation and evaluation of lansoprazole niosome

Naresh Ahuja, Vipin Saini, Vijay Kumar Bishnoi, Atul Garg, Monika Hisoria, Joyati Sharma, Kunal Nepali

研究成果: 雜誌貢獻文章同行評審

6 引文 斯高帕斯(Scopus)

摘要

The niosomes formulation has got various advantages over conventional dosage forms; these stay in the blood for longer time then conventional and can thus greatly improve the therapeutic effect of drug. In many diseases (e. g. cancer) a considerable therapeutic advantage could be gained if drugs were delivered in selective and controlled manner to their target sites. The noisome are prepared by reverse phase evaporation method using a homogenizers. Non-ionic surfactant based vesicles used as vesicles for drug formulation have been found to reduce the systemic toxicity of many drugs. Lansoprazole was selected as candidate drug, it is antacid and antiulcer agents. Niosomes are characterized for its size rang, entrapment efficiency and in-vitro release of drug. For release study the phosphate buffer saline pH 8. 6 was used and the samples were assayed by UV.
原文英語
頁(從 - 到)561-563
頁數3
期刊Rasayan Journal of Chemistry
1
發行號3
出版狀態已發佈 - 一月 1 2008
對外發佈

ASJC Scopus subject areas

  • 化學 (全部)
  • 生物化學
  • 化學工程 (全部)
  • 能源(全部)
  • 藥理學、毒理學和藥劑學 (全部)

指紋

深入研究「Formulation and evaluation of lansoprazole niosome」主題。共同形成了獨特的指紋。

引用此