Flame sprayed zinc doped hydroxyapatite coating with antibacterial and biocompatible properties

Yung Chin Yang, Chien Chung Chen, Jhong Bo Wang, Yen Ching Wang, Feng Huei Lin

研究成果: 雜誌貢獻文章同行評審

22 引文 斯高帕斯(Scopus)

摘要

Hydroxyapatite (HA) has good biocompatibility, high strength and low fracture toughness. It is often used as the main material for artificial bones in bioceramics because of the similar composition. In this study, we prepared zinc-doped hydroxyapatite by the co-precipitation method to produce artificial bone material has antibacterial properties, for use in post joint surgery to inhibit bacterial infection or proliferation and ultimately the incidence of osteomyelitis. The co-precipitation method prepared hydroxyapatite with different concentrations of zinc chloride. The experimental results revealed that after sintering, it has some new phases generated of ZnO and CaZn2(PO4)2 when we add zinc chloride that concentration reaches 0.15M. The minimum inhibition zone revealed the antibacterial ability of Zinc-HA increased when the concentration of zinc chloride increased from 0.0125M to 0.15M. The granulated powder of zinc-doped hydroxyapatite was coated on the titanium substrate by the flame-spraying method. The Zinc-HA coating was found with good biocompatibility and antibacterial ability in the biological and antibacterial test.
原文英語
期刊Ceramics International
DOIs
出版狀態接受/付印 - 2017

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Process Chemistry and Technology
  • Surfaces, Coatings and Films
  • Materials Chemistry

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