Fatty acid components in Asian female patients with irritable bowel syndrome

Chian Sem Chua, Shih Yi Huang, Chiao Wen Cheng, Chyi Huey Bai, Chien Yeh Hsu, Hung Wen Chiu, Jung Lung Hsu

研究成果: 雜誌貢獻文章

摘要

Abdominal pain is one of the key symptoms of irritable bowel syndrome (IBS). Studies have indicated an increase in the incidence of IBS in Asia. However, yet the pathophysiology of this disease remains unknown. Women are more likely to develop the condition than men, especially the constipation-predominant type. Essential fatty acid (EFA) malnutrition is one of several theories discussing the mechanism of IBS. The authors hypothesized that significant EFA deficiency may cause abdominal pain in patients with IBS. However, because patterns in the oral intake of EFAs differ between cultures, the authors narrowed this study to examine the nutritional status of Asian female patients with IBS The authors investigated Asian female patients with IBS and compared them with a group of healthy controls. Thirty patients with IBS and 39 healthy individuals were included in this study. The participants' age, height, weight, and waist size were recorded. The 24-item Hamilton Depression Rating Scale was documented. Both erythrocyte and plasma fatty acid content were analyzed through gas-liquid chromatography. The authors found that patients with IBS exhibited significantly higher scores for depression, higher proportions of plasma saturated fatty acids and monounsaturated fatty acids, and lower proportions of docosahexaenoic acid and total omega-3 polyunsaturated fatty acids in plasma are associated with IBS in Asian female patients. Further study is indicated to confirm the causality of this association.
原文英語
文章編號e9094
期刊Medicine (United States)
96
發行號49
DOIs
出版狀態已發佈 - 十二月 1 2017

指紋

Irritable Bowel Syndrome
Fatty Acids
Essential Fatty Acids
Abdominal Pain
Monounsaturated Fatty Acids
Docosahexaenoic Acids
Omega-3 Fatty Acids
Constipation
Nutritional Status
Unsaturated Fatty Acids
Malnutrition
Causality
Gas Chromatography
Erythrocytes
Weights and Measures
Control Groups
Incidence

ASJC Scopus subject areas

  • Medicine(all)

引用此文

Fatty acid components in Asian female patients with irritable bowel syndrome. / Chua, Chian Sem; Huang, Shih Yi; Cheng, Chiao Wen; Bai, Chyi Huey; Hsu, Chien Yeh; Chiu, Hung Wen; Hsu, Jung Lung.

於: Medicine (United States), 卷 96, 編號 49, e9094, 01.12.2017.

研究成果: 雜誌貢獻文章

Chua, Chian Sem ; Huang, Shih Yi ; Cheng, Chiao Wen ; Bai, Chyi Huey ; Hsu, Chien Yeh ; Chiu, Hung Wen ; Hsu, Jung Lung. / Fatty acid components in Asian female patients with irritable bowel syndrome. 於: Medicine (United States). 2017 ; 卷 96, 編號 49.
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